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    CG9444 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41175, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9444provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037730
    Locus tag
    Dmel_CG9444
    See related
    AllianceGenome:FB:FBgn0037730
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9444
    Summary
    Predicted to enable dipeptide transmembrane transporter activity. Predicted to be involved in dipeptide import across plasma membrane. Predicted to be located in membrane. Predicted to be active in apical plasma membrane. Is expressed in several structures, including Malpighian tubule primordium; adult head; embryonic/larval fat body; embryonic/larval midgut; and epithelium. Orthologous to human SLC15A2 (solute carrier family 15 member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9444 in Genome Data Viewer
    Location:
    85E4-85E4; 3-49 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (9681415..9684264, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5507137..5509986, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Neprilysin-like 12 Neighboring gene p23 Neighboring gene nmdyn-D7 Neighboring gene eclair Neighboring gene uncharacterized protein Neighboring gene Uncoordinated 115b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Oligopeptide Transporters of the SLC15 Family Are Dispensable for Peptidoglycan Sensing and Transport in Drosophila. Capo F, et al. J Innate Immun, 2017. PMID 28715804, Free PMC Article
    2. SLC46 Family Transporters Facilitate Cytosolic Innate Immune Recognition of Monomeric Peptidoglycans. Paik D, et al. J Immunol, 2017 Jul 1. PMID 28539433, Free PMC Article
    3. A phylogenetic analysis between humans and D. melanogaster: A repertoire of solute carriers in humans and flies. Ceder MM, et al. Gene, 2022 Jan 30. PMID 34673204
    4. Function-informed transcriptome analysis of Drosophila renal tubule. Wang J, et al. Genome Biol, 2004. PMID 15345053, Free PMC Article
    5. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables dipeptide transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in dipeptide import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in oligopeptide transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in apical plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9444-PA
    CG9444-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      9681415..9684264 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275502.1 → NP_001262431.1  uncharacterized protein Dmel_CG9444, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262431.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SX48, Q9VH93
      Conserved Domains (2) summary
      COG3104
      Location:68 → 524
      PTR2; Dipeptide/tripeptide permease [Amino acid transport and metabolism]
      cl21472
      Location:137 → 488
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

    2. NM_141670.4 → NP_649927.2  uncharacterized protein Dmel_CG9444, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649927.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SX48, Q9VH93
      Related
      FBpp0081577
      Conserved Domains (2) summary
      COG3104
      Location:68 → 524
      PTR2; Dipeptide/tripeptide permease [Amino acid transport and metabolism]
      cl21472
      Location:137 → 488
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SX48 Q8SX48
    Q9VH93 Q9VH93

    Gene LinkOut

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