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    Naa20B N(alpha)-acetyltransferase 20 B [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318982, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Naa20Bprovided by FlyBase
    Official Full Name
    N(alpha)-acetyltransferase 20 Bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051851
    Locus tag
    Dmel_CG31851
    See related
    AllianceGenome:FB:FBgn0051851
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG16821; CG31851; Dmel\CG31851; Naa20; NAA20
    Summary
    Predicted to enable peptide alpha-N-acetyltransferase activity. Predicted to be involved in regulation of actin cytoskeleton organization. Predicted to be part of NatB complex. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Naa20B in Genome Data Viewer
    Location:
    34B2-34B3; 2-48 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (13257477..13258644)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (13257477..13258644)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene lethal (2) k05911 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Absence of N-terminal acetyltransferase diversification during evolution of eukaryotic organisms. Rathore OS, et al. Sci Rep, 2016 Feb 10. PMID 26861501, Free PMC Article
    2. A genome-wide analysis of immune responses in Drosophila. Irving P, et al. Proc Natl Acad Sci U S A, 2001 Dec 18. PMID 11742098, Free PMC Article
    3. Metabolic regulation of proteome stability via N-terminal acetylation controls male germline stem cell differentiation and reproduction. François CM, et al. Nat Commun, 2023 Oct 23. PMID 37872135, Free PMC Article
    4. Immunity-related genes and gene families in Anopheles gambiae. Christophides GK, et al. Science, 2002 Oct 4. PMID 12364793
    5. Functional relevance of genes predicted to be affected by epigenetic alterations in atypical teratoid/rhabdoid tumors. Tegeder I, et al. J Neurooncol, 2019 Jan. PMID 30446899

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptide alpha-N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of NatB complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    N(alpha)-acetyltransferase 20 B
    Names
    CG31851-PA
    CG31851-PB
    N(alpha)-acetyltransferase 20
    Naa20B-PA
    Naa20B-PB
    NP_001285885.1
    NP_723798.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      13257477..13258644
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298956.1 → NP_001285885.1  N(alpha)-acetyltransferase 20 B, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285885.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IP78
      Conserved Domains (2) summary
      COG0456
      Location:27 → 158
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
      pfam00583
      Location:50 → 137
      Acetyltransf_1; Acetyltransferase (GNAT) family

    2. NM_165032.2 → NP_723798.1  N(alpha)-acetyltransferase 20 B, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723798.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IP78
      Related
      FBpp0080033
      Conserved Domains (2) summary
      COG0456
      Location:27 → 158
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
      pfam00583
      Location:50 → 137
      Acetyltransf_1; Acetyltransferase (GNAT) family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IP78 Q8IP78

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