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    BC034090 cDNA sequence BC034090 [ Mus musculus (house mouse) ]

    Gene ID: 207792, updated on 27-Nov-2024

    Summary

    Official Symbol
    BC034090provided by MGI
    Official Full Name
    cDNA sequence BC034090provided by MGI
    Primary source
    MGI:MGI:2672904
    See related
    Ensembl:ENSMUSG00000033722 AllianceGenome:MGI:2672904
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA1614; 6820428L09
    Summary
    Predicted to be involved in centrosome cycle; establishment or maintenance of cell polarity; and regulation of cellular localization. Predicted to be active in apical plasma membrane; cell cortex; and nucleus. Orthologous to human KIAA1614 (KIAA1614). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in kidney adult (RPKM 13.3), adrenal adult (RPKM 6.5) and 19 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See BC034090 in Genome Data Viewer
    Location:
    1 G3; 1 66.47 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (155088217..155123504, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (155212471..155245639, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30922 Neighboring gene STARR-positive B cell enhancer ABC_E2569 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:157001032-157001362 Neighboring gene STARR-positive B cell enhancer ABC_E500 Neighboring gene major histocompatibility complex, class I-related Neighboring gene syntaxin 6 Neighboring gene high mobility group protein B3 pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:157081058-157081259 Neighboring gene predicted gene, 31102 Neighboring gene STARR-positive B cell enhancer ABC_E7760 Neighboring gene xenotropic and polytropic retrovirus receptor 1 Neighboring gene predicted gene, 17974 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:157242079-157242280 Neighboring gene STARR-positive B cell enhancer mm9_chr1:157264431-157264732 Neighboring gene STARR-seq mESC enhancer starr_02724 Neighboring gene predicted gene, 31713

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in centrosome cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in establishment or maintenance of cell polarity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of cellular localization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in apical plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cell cortex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein KIAA1614 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001370865.1NP_001357794.1  uncharacterized protein KIAA1614 homolog

      Status: VALIDATED

      Source sequence(s)
      AC110268
      Consensus CDS
      CCDS87895.1
      UniProtKB/TrEMBL
      A0A087WP46
      Related
      ENSMUSP00000139623.2, ENSMUST00000186156.7
      Conserved Domains (2) summary
      cd00992
      Location:11141195
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15737
      Location:337461
      DUF4685; Domain of unknown function (DUF4685)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      155088217..155123504 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006530031.5XP_006530094.1  uncharacterized protein KIAA1614 homolog isoform X2

      Conserved Domains (2) summary
      cd00992
      Location:10461127
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15737
      Location:337461
      DUF4685; Domain of unknown function (DUF4685)
    2. XM_148974.13XP_148974.3  uncharacterized protein KIAA1614 homolog isoform X1

      Conserved Domains (2) summary
      cd00992
      Location:10831164
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15737
      Location:306430
      DUF4685; Domain of unknown function (DUF4685)
    3. XM_030252447.1XP_030108307.1  uncharacterized protein KIAA1614 homolog isoform X3

      UniProtKB/TrEMBL
      F6T2X5, Q8K058
      Related
      ENSMUSP00000037456.5, ENSMUST00000035914.5
      Conserved Domains (2) summary
      cd00992
      Location:752833
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15737
      Location:199
      DUF4685; Domain of unknown function (DUF4685)
    4. XM_006530035.4XP_006530098.1  uncharacterized protein KIAA1614 homolog isoform X3

      UniProtKB/TrEMBL
      F6T2X5, Q8K058
      Conserved Domains (2) summary
      cd00992
      Location:752833
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15737
      Location:199
      DUF4685; Domain of unknown function (DUF4685)
    5. XM_036163040.1XP_036018933.1  uncharacterized protein KIAA1614 homolog isoform X3

      UniProtKB/TrEMBL
      F6T2X5, Q8K058
      Conserved Domains (2) summary
      cd00992
      Location:752833
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15737
      Location:199
      DUF4685; Domain of unknown function (DUF4685)
    6. XM_006530036.5XP_006530099.1  uncharacterized protein KIAA1614 homolog isoform X4

      UniProtKB/TrEMBL
      Q8K058
      Conserved Domains (2) summary
      cd00992
      Location:687768
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15737
      Location:134
      DUF4685; Domain of unknown function (DUF4685)
    7. XM_036163046.1XP_036018939.1  uncharacterized protein KIAA1614 homolog isoform X5

      UniProtKB/TrEMBL
      Q8K058
      Conserved Domains (2) summary
      cd00992
      Location:619700
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15737
      Location:134
      DUF4685; Domain of unknown function (DUF4685)

    RNA

    1. XR_003954294.2 RNA Sequence

    2. XR_004941304.1 RNA Sequence

    3. XR_004941302.1 RNA Sequence

    4. XR_004941303.1 RNA Sequence

    5. XR_387502.5 RNA Sequence

    6. XR_878643.4 RNA Sequence