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    A1BG alpha-1-B glycoprotein [ Homo sapiens (human) ]

    Gene ID: 1, updated on 10-Dec-2024

    Summary

    Official Symbol
    A1BGprovided by HGNC
    Official Full Name
    alpha-1-B glycoproteinprovided by HGNC
    Primary source
    HGNC:HGNC:5
    See related
    Ensembl:ENSG00000121410 MIM:138670; AllianceGenome:HGNC:5
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    A1B; ABG; GAB; HYST2477
    Summary
    The protein encoded by this gene is a plasma glycoprotein of unknown function. The protein shows sequence similarity to the variable regions of some immunoglobulin supergene family member proteins. [provided by RefSeq, Jul 2008]
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See A1BG in Genome Data Viewer
    Location:
    19q13.43
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (58345183..58353492, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (61441599..61449907, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (58856549..58864858, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105372480 Neighboring gene zinc finger protein 470 pseudogene Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:58838245-58838987 Neighboring gene zinc finger and SCAN domain containing 22 Neighboring gene microRNA 6806 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:58849877-58850378 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:58858160-58858660 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:58858661-58859161 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15186 Neighboring gene A1BG antisense RNA 1 Neighboring gene zinc finger protein 446 pseudogene Neighboring gene zinc finger protein 497 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:58873404-58873952 Neighboring gene ZNF497 antisense RNA 1 Neighboring gene RNA, 5S ribosomal pseudogene 473

    Genomic regions, transcripts, and products

    Expression

    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    General gene information

    Potential readthrough

    Included gene: ZNF497

    Clone Names

    • DKFZp686F0970

    Gene Ontology Provided by GOA

    General protein information

    Preferred Names
    alpha-1B-glycoprotein
    Names
    HEL-S-163pA
    epididymis secretory sperm binding protein Li 163pA

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_130786.4 → NP_570602.2  alpha-1B-glycoprotein precursor

      See identical proteins and their annotated locations for NP_570602.2

      Status: REVIEWED

      Source sequence(s)
      AB073611, AC012313, AK056201
      Consensus CDS
      CCDS12976.1
      UniProtKB/Swiss-Prot
      A8K052, P04217, Q68CK0, Q8IYJ6, Q96P39
      UniProtKB/TrEMBL
      V9HWD8
      Related
      ENSP00000263100.2, ENST00000263100.8
      Conserved Domains (4) summary
      cd05751
      Location:401 → 493
      Ig1_LILRB1_like; First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins
      smart00410
      Location:218 → 280
      IG_like; Immunoglobulin like
      pfam13895
      Location:210 → 301
      Ig_2; Immunoglobulin domain
      cl11960
      Location:28 → 110
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      58345183..58353492 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      61441599..61449907 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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