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    Prxl2c peroxiredoxin like 2C [ Mus musculus (house mouse) ]

    Gene ID: 66129, updated on 9-Dec-2024

    Summary

    Official Symbol
    Prxl2cprovided by MGI
    Official Full Name
    peroxiredoxin like 2Cprovided by MGI
    Primary source
    MGI:MGI:1913379
    See related
    Ensembl:ENSMUSG00000021482 AllianceGenome:MGI:1913379
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Aaed1; 1110018J18Rik
    Summary
    Predicted to be involved in positive regulation of ERK1 and ERK2 cascade and positive regulation of glycolytic process. Orthologous to human PRXL2C (peroxiredoxin like 2C). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in lung adult (RPKM 20.0), liver adult (RPKM 19.8) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Prxl2c in Genome Data Viewer
    Location:
    13 B3; 13 33.26 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (64437612..64460524, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (64289798..64312710, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene CDC14 cell division cycle 14B Neighboring gene STARR-seq mESC enhancer starr_34826 Neighboring gene predicted gene, 46424 Neighboring gene RIKEN cDNA 1810034E14 gene Neighboring gene STARR-seq mESC enhancer starr_34827 Neighboring gene STARR-positive B cell enhancer ABC_E8894 Neighboring gene STARR-positive B cell enhancer ABC_E1879 Neighboring gene predicted gene, 31128 Neighboring gene STARR-positive B cell enhancer ABC_E3084 Neighboring gene cathepsin L

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    peroxiredoxin-like 2C
    Names
    AhpC/TSA antioxidant enzyme domain containing 1
    UPF0308 protein C9orf21 homolog
    ahpC/TSA antioxidant enzyme domain-containing protein 1
    thioredoxin-like protein AAED1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025370.3NP_079646.1  peroxiredoxin-like 2C

      See identical proteins and their annotated locations for NP_079646.1

      Status: VALIDATED

      Source sequence(s)
      AK003782, AK145867, AK168701, CT030159
      Consensus CDS
      CCDS26599.1
      UniProtKB/Swiss-Prot
      Q3UFP2, Q9CVT8, Q9D1A0
      UniProtKB/TrEMBL
      Q3TGK4
      Related
      ENSMUSP00000152323.2, ENSMUST00000222570.2
      Conserved Domains (1) summary
      cd02970
      Location:34195
      PRX_like2; Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      64437612..64460524 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)