U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Magoh mago homolog, exon junction complex core component [ Mus musculus (house mouse) ]

    Gene ID: 17149, updated on 9-Dec-2024

    Summary

    Official Symbol
    Magohprovided by MGI
    Official Full Name
    mago homolog, exon junction complex core componentprovided by MGI
    Primary source
    MGI:MGI:1330312
    See related
    Ensembl:ENSMUSG00000028609 AllianceGenome:MGI:1330312
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mos2; Mago-m
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in RNA splicing and regulation of gene expression. Predicted to be located in nucleus. Predicted to be part of catalytic step 2 spliceosome and exon-exon junction subcomplex mago-y14. Is expressed in intestine; liver; spleen; telencephalon; and testis. Orthologous to human MAGOH (mago homolog, exon junction complex subunit). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in CNS E11.5 (RPKM 75.7), placenta adult (RPKM 62.8) and 27 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Magoh in Genome Data Viewer
    Location:
    4 C7; 4 50.18 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (107736952..107744621)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (107879755..107887424)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene low density lipoprotein receptor-related protein 8, apolipoprotein e receptor, opposite strand 3 Neighboring gene STARR-positive B cell enhancer ABC_E7978 Neighboring gene low density lipoprotein receptor-related protein 8, apolipoprotein e receptor, opposite strand 2 Neighboring gene low density lipoprotein receptor-related protein 8, apolipoprotein e receptor Neighboring gene STARR-positive B cell enhancer ABC_E4643 Neighboring gene STARR-positive B cell enhancer ABC_E1649 Neighboring gene CXXC motif containing zinc binding protein Neighboring gene carnitine palmitoyltransferase 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Chemically induced (ENU) (1)  1 citation
    • Endonuclease-mediated (1) 
    • Gene trapped (2) 
    • Targeted (3)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of catalytic step 2 spliceosome IEA
    Inferred from Electronic Annotation
    more info
     
    part_of catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol NAS
    Non-traceable Author Statement
    more info
    PubMed 
    part_of exon-exon junction complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of exon-exon junction complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of exon-exon junction subcomplex mago-y14 ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus NAS
    Non-traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    protein mago nashi homolog
    Names
    mago-nashi homolog, proliferation-associated

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001282737.1NP_001269666.1  protein mago nashi homolog

      See identical proteins and their annotated locations for NP_001269666.1

      Status: VALIDATED

      Source sequence(s)
      AK011512, BY134232
      Consensus CDS
      CCDS18441.1
      UniProtKB/Swiss-Prot
      A2A8E0, P61327
      Related
      ENSMUSP00000030348.6, ENSMUST00000030348.6
      Conserved Domains (1) summary
      cd11295
      Location:4146
      Mago_nashi; Mago nashi proteins, integral members of the exon junction complex

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      107736952..107744621
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)