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    Cog6 component of oligomeric golgi complex 6 [ Mus musculus (house mouse) ]

    Gene ID: 67542, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cog6provided by MGI
    Official Full Name
    component of oligomeric golgi complex 6provided by MGI
    Primary source
    MGI:MGI:1914792
    See related
    Ensembl:ENSMUSG00000027742 AllianceGenome:MGI:1914792
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA1134; 4933405E16Rik
    Summary
    Predicted to be involved in Golgi organization; glycosylation; and retrograde transport, vesicle recycling within Golgi. Predicted to be located in Golgi membrane. Predicted to be part of Golgi transport complex. Is expressed in retina outer nuclear layer. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIl. Orthologous to human COG6 (component of oligomeric golgi complex 6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 39.3), heart adult (RPKM 17.2) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Cog6 in Genome Data Viewer
    Location:
    3 C; 3 24.1 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (52889544..52924644, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (52982123..53017223, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30351 Neighboring gene STARR-positive B cell enhancer ABC_E2070 Neighboring gene predicted gene, 30402 Neighboring gene LHFPL tetraspan subfamily member 6 Neighboring gene STARR-seq mESC enhancer starr_07650 Neighboring gene STARR-seq mESC enhancer starr_07651 Neighboring gene STARR-seq mESC enhancer starr_07652 Neighboring gene STARR-seq mESC enhancer starr_07654 Neighboring gene predicted gene, 40048

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in Golgi organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in glycosylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in glycosylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in intra-Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intra-Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in retrograde transport, vesicle recycling within Golgi ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of Golgi transport complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of Golgi transport complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of Golgi transport complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    conserved oligomeric Golgi complex subunit 6
    Names
    COG complex subunit 6
    conserved oligomeric Golgi complex protein 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026225.3NP_080501.2  conserved oligomeric Golgi complex subunit 6

      See identical proteins and their annotated locations for NP_080501.2

      Status: VALIDATED

      Source sequence(s)
      AK016663, AK153320
      Consensus CDS
      CCDS50905.1
      UniProtKB/Swiss-Prot
      Q8BSN7, Q8CHB1, Q8R3I3, Q9CTA8
      UniProtKB/TrEMBL
      A0A0R4J0L5
      Related
      ENSMUSP00000048603.5, ENSMUST00000036665.10
      Conserved Domains (1) summary
      pfam06419
      Location:56652
      COG6; Conserved oligomeric complex COG6

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      52889544..52924644 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)