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    Slc50a1 solute carrier family 50 (sugar transporter), member 1 [ Mus musculus (house mouse) ]

    Gene ID: 19729, updated on 9-Dec-2024

    Summary

    Official Symbol
    Slc50a1provided by MGI
    Official Full Name
    solute carrier family 50 (sugar transporter), member 1provided by MGI
    Primary source
    MGI:MGI:107417
    See related
    Ensembl:ENSMUSG00000027953 AllianceGenome:MGI:107417
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rga; Rag1ap1; MmSWEET1
    Summary
    Predicted to enable glucoside transmembrane transporter activity and sugar transmembrane transporter activity. Predicted to be involved in carbohydrate transport. Predicted to be located in Golgi apparatus and plasma membrane. Predicted to be active in membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and integumental system. Orthologous to human SLC50A1 (solute carrier family 50 member 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in colon adult (RPKM 117.8), lung adult (RPKM 98.3) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Slc50a1 in Genome Data Viewer
    Location:
    3 F1; 3 39.04 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (89175553..89177878, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (89268246..89270591, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene tripartite motif-containing 46 Neighboring gene keratinocyte associated protein 2 Neighboring gene STARR-positive B cell enhancer ABC_E4552 Neighboring gene dolichyl-phosphate mannosyltransferase polypeptide 3 Neighboring gene ephrin A1 Neighboring gene VISTA enhancer mm1415 Neighboring gene predicted gene, 33845

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2) 

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables glucoside transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables glucoside transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables sugar transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables sugar transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in carbohydrate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in carbohydrate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in glucoside transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endomembrane system ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    sugar transporter SWEET1
    Names
    RAG1-activating protein 1
    probable sugar transporter RAG1AP1
    recombination activating gene 1 activating protein 1
    recombination activating gene 1 gene activation
    solute carrier family 50 member 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001410551.1NP_001397480.1  sugar transporter SWEET1 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC132327
    2. NM_001410552.1NP_001397481.1  sugar transporter SWEET1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC132327
    3. NM_001410553.1NP_001397482.1  sugar transporter SWEET1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC132327
      Related
      ENSMUST00000148095.2
    4. NM_001410554.1NP_001397483.1  sugar transporter SWEET1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC132327
      Related
      ENSMUST00000144777.8
    5. NM_001410555.1NP_001397484.1  sugar transporter SWEET1 isoform 4 precursor

      Status: VALIDATED

      Source sequence(s)
      AC132327
      UniProtKB/TrEMBL
      D3YXA7
      Related
      ENSMUSP00000103084.2, ENSMUST00000107460.8
    6. NM_001410556.1NP_001397485.1  sugar transporter SWEET1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC132327
    7. NM_001410557.1NP_001397486.1  sugar transporter SWEET1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC132327
    8. NM_001410558.1NP_001397487.1  sugar transporter SWEET1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC132327
    9. NM_001410559.1NP_001397488.1  sugar transporter SWEET1 isoform 6 precursor

      Status: VALIDATED

      Source sequence(s)
      AC132327
    10. NM_001410560.1NP_001397489.1  sugar transporter SWEET1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC132327
    11. NM_009057.4NP_033083.2  sugar transporter SWEET1 isoform 1 precursor

      See identical proteins and their annotated locations for NP_033083.2

      Status: VALIDATED

      Source sequence(s)
      AC132327
      Consensus CDS
      CCDS17500.1
      UniProtKB/Swiss-Prot
      Q62275, Q9CXK4
      Related
      ENSMUSP00000029565.5, ENSMUST00000029565.11
      Conserved Domains (1) summary
      pfam03083
      Location:995
      MtN3_slv; Sugar efflux transporter for intercellular exchange

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      89175553..89177878 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_004941298.1 RNA Sequence

      Related
      ENSMUST00000133575.8