U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Czib CXXC motif containing zinc binding protein [ Mus musculus (house mouse) ]

    Gene ID: 74098, updated on 9-Dec-2024

    Summary

    Official Symbol
    Czibprovided by MGI
    Official Full Name
    CXXC motif containing zinc binding proteinprovided by MGI
    Primary source
    MGI:MGI:1921348
    See related
    Ensembl:ENSMUSG00000028608 AllianceGenome:MGI:1921348
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    0610037L13Rik; 1110008H16Rik
    Summary
    Predicted to enable zinc ion binding activity. Orthologous to human CZIB (CXXC motif containing zinc binding protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in bladder adult (RPKM 22.6), limb E14.5 (RPKM 18.0) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Czib in Genome Data Viewer
    Location:
    4 C7; 4 50.18 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (107746982..107755000)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (107889785..107897803)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene low density lipoprotein receptor-related protein 8, apolipoprotein e receptor, opposite strand 2 Neighboring gene low density lipoprotein receptor-related protein 8, apolipoprotein e receptor Neighboring gene STARR-positive B cell enhancer ABC_E4643 Neighboring gene STARR-positive B cell enhancer ABC_E1649 Neighboring gene mago homolog, exon junction complex core component Neighboring gene carnitine palmitoyltransferase 2 Neighboring gene predicted gene, 40221

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables zinc ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    CXXC motif containing zinc binding protein
    Names
    UPF0587 protein C1orf123 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347160.1NP_001334089.1  CXXC motif containing zinc binding protein isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1.
      Source sequence(s)
      AL611936
      Consensus CDS
      CCDS84769.1
      UniProtKB/Swiss-Prot
      A2A8E3, A2A8E5, Q8BHG2, Q8C7D6, Q9D1H2, Q9DCH5
      UniProtKB/TrEMBL
      A2A8E2
      Related
      ENSMUSP00000114234.2, ENSMUST00000135454.8
      Conserved Domains (1) summary
      pfam05907
      Location:6157
      DUF866; Eukaryotic protein of unknown function (DUF866)
    2. NM_028754.2NP_083030.1  CXXC motif containing zinc binding protein isoform 1

      See identical proteins and their annotated locations for NP_083030.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AL611936
      Consensus CDS
      CCDS18442.1
      UniProtKB/Swiss-Prot
      Q8BHG2
      Related
      ENSMUSP00000119565.2, ENSMUST00000125107.8
      Conserved Domains (1) summary
      pfam05907
      Location:42193
      DUF866; Eukaryotic protein of unknown function (DUF866)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      107746982..107755000
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030253839.1XP_030109699.1  CXXC motif containing zinc binding protein isoform X3

      UniProtKB/TrEMBL
      B7ZC72
      Related
      ENSMUSP00000102338.4, ENSMUST00000106727.10
      Conserved Domains (1) summary
      pfam05907
      Location:8136
      DUF866; Eukaryotic protein of unknown function (DUF866)
    2. XM_036164493.1XP_036020386.1  CXXC motif containing zinc binding protein isoform X5

      Conserved Domains (1) summary
      pfam05907
      Location:3108
      DUF866; Eukaryotic protein of unknown function (DUF866)
    3. XM_006503440.4XP_006503503.1  CXXC motif containing zinc binding protein isoform X4

      Conserved Domains (1) summary
      pfam05907
      Location:4128
      DUF866; Eukaryotic protein of unknown function (DUF866)
    4. XM_006503437.4XP_006503500.1  CXXC motif containing zinc binding protein isoform X1

      UniProtKB/TrEMBL
      A2A8E2
      Conserved Domains (1) summary
      pfam05907
      Location:9157
      DUF866; Eukaryotic protein of unknown function (DUF866)
    5. XM_006503439.3XP_006503502.1  CXXC motif containing zinc binding protein isoform X2

      UniProtKB/TrEMBL
      B7ZC72
      Conserved Domains (1) summary
      pfam05907
      Location:9137
      DUF866; Eukaryotic protein of unknown function (DUF866)