Fabp6 fatty acid binding protein 6 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Fabp6provided by RGD
Official Full Name: fatty acid binding protein 6provided by RGD
Primary source: RGD:2592
See related: AllianceGenome:RGD:2592
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: IBABP
Summary: Enables fatty acid binding activity. Involved in steroid metabolic process. Predicted to be located in cytoplasm and membrane. Predicted to be active in cytosol and nucleus. Orthologous to human FABP6 (fatty acid binding protein 6). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Adrenal (RPKM 37.3), Thymus (RPKM 7.5) and 1 other tissue See more
Orthologs: human mouse all
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Genomic context

Location:: 10q21

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (28565054..28569727, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (28063603..28068276, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (29191621..29196593, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The intronless Fabp6 segment, which might be a pseudogene of Fabp6, was localized on rat chromosome 15.
Title: Sequencing and chromosomal localization of Fabp6 and an intronless Fabp6 segment in the rat.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables fatty acid binding	IBA Inferred from Biological aspect of Ancestor more info
enables fatty acid binding	IDA Inferred from Direct Assay more info	PubMed
enables lipid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in fatty acid transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in steroid metabolic process	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: gastrotropin

Names: 14 kDa bile acid-binding protein; Fatty acid binding protein 6 (bile acid-binding protein); GT; I-15P; I-BABP; ILBP; fatty acid binding protein 6, ileal; ileal lipid-binding protein; intestinal 15 kDa protein; strain SHR/OlaIpcv fatty acid binding protein 6 (Fabp6) pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_017098.2 → NP_058794.2 gastrotropin

Status: PROVISIONAL

Source sequence(s)

JAXUCZ010000010

UniProtKB/Swiss-Prot

P80020

UniProtKB/TrEMBL

A6HDN2, G3V6H6

Conserved Domains (1) summary

pfam14651
Location:1 → 128

Lipocalin_7; Lipocalin / cytosolic fatty-acid binding protein family