BioGRID CRISPR Screen Phenotypes (12 hits/1267 screens)
Find tests for this gene in the NIH Genetic Testing Registry (GTR)
Review eQTL and phenotype association data in this region using PheGenI
EBI GWAS Catalog
Description |
Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death. |
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. |
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. |
Genetic determinants of P wave duration and PR segment. |
Genetic variation in SCN10A influences cardiac conduction. |
Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk. |
Genome-wide association studies of the PR interval in African Americans. |
Genome-wide association study of electrocardiographic parameters identifies a new association for PR interval and confirms previously reported associations. |
Genome-wide association study of PR interval. |
Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science. |
Identification of three novel genetic variations associated with electrocardiographic traits (QRS duration and PR interval) in East Asians. |
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. |
Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts. |
Several common variants modulate heart rate, PR interval and QRS duration. |