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    Tmem192 transmembrane protein 192 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361137, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tmem192provided by RGD
    Official Full Name
    transmembrane protein 192provided by RGD
    Primary source
    RGD:1309341
    See related
    EnsemblRapid:ENSRNOG00000030199 AllianceGenome:RGD:1309341
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309341
    Summary
    Predicted to enable protein homodimerization activity. Predicted to be located in several cellular components, including endosome; lysosome; and perinuclear region of cytoplasm. Predicted to be active in late endosome and lysosomal membrane. Orthologous to human TMEM192 (transmembrane protein 192). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 88.3), Kidney (RPKM 87.0) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tmem192 in Genome Data Viewer
    Location:
    16p13
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (29506658..29527553, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (24740166..24760994, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (26620525..26642537, complement)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene tripartite motif-containing 75 like, pseudogene 1 Neighboring gene tripartite motif containing 60 Neighboring gene kelch-like family member 2 Neighboring gene U6 spliceosomal RNA Neighboring gene methylsterol monooxygenase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    NOT located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    NOT located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in late endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in late endosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in late endosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in lysosomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in lysosomal membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in lysosomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    NOT located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    NOT located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014141.1NP_001014163.1  transmembrane protein 192

      See identical proteins and their annotated locations for NP_001014163.1

      Status: PROVISIONAL

      Source sequence(s)
      BC086402
      UniProtKB/Swiss-Prot
      Q5U1Y0
      UniProtKB/TrEMBL
      A0A8I6AEY9, A6KFN6
      Related
      ENSRNOP00000102231.1, ENSRNOT00000125730.1
      Conserved Domains (1) summary
      pfam14802
      Location:26259
      TMEM192; TMEM192 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      29506658..29527553 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063275514.1XP_063131584.1  transmembrane protein 192 isoform X1