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    Snupn snurportin 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 316108, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Snupnprovided by RGD
    Official Full Name
    snurportin 1provided by RGD
    Primary source
    RGD:1303191
    See related
    EnsemblRapid:ENSRNOG00000005426 AllianceGenome:RGD:1303191
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Rnut1
    Summary
    Predicted to enable RNA cap binding activity. Predicted to be involved in RNA import into nucleus. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be part of NLS-dependent protein nuclear import complex. Orthologous to human SNUPN (snurportin 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 42.2), Lung (RPKM 38.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Snupn in Genome Data Viewer
    Location:
    8q24
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (66242940..66286651)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (57347412..57388345)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (61614798..61654809)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S15a like 7 Neighboring gene IMP U3 small nucleolar ribonucleoprotein 3 Neighboring gene uncharacterized LOC103693102 Neighboring gene protein tyrosine phosphatase, non-receptor type 9 Neighboring gene uncharacterized LOC102553607 Neighboring gene uncharacterized LOC120094171 Neighboring gene SIN3 transcription regulator family member A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. CRM1-mediated recycling of snurportin 1 to the cytoplasm. Paraskeva E, et al. J Cell Biol, 1999 Apr 19. PMID 10209022, Free PMC Article
    2. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC95000

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA cap binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables nuclear import signal receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA import into nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in RNA import into nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cytoskeleton organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein complex oligomerization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein complex oligomerization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein import into nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein tetramerization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein tetramerization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in snRNA import into nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of NLS-dependent protein nuclear import complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of nuclear cap binding complex TAS
    Traceable Author Statement
    more info
    		 PubMed 
    part_of nuclear pore TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    snurportin-1
    Names
    RNA U transporter 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004270.1 → NP_001004270.1  snurportin-1

      See identical proteins and their annotated locations for NP_001004270.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079451
      UniProtKB/Swiss-Prot
      Q68FP5
      UniProtKB/TrEMBL
      A6J4S2
      Related
      ENSRNOP00000110228.1, ENSRNOT00000170389.1
      Conserved Domains (2) summary
      cd09232
      Location:98 → 282
      Snurportin-1_C; C-terminal m3G cap-binding domain of nuclear import adaptor snurportin-1
      pfam11538
      Location:25 → 64
      Snurportin1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      66242940..66286651
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063265671.1 → XP_063121741.1  snurportin-1 isoform X2

    2. XM_063265667.1 → XP_063121737.1  snurportin-1 isoform X2

    3. XM_063265672.1 → XP_063121742.1  snurportin-1 isoform X8

    4. XM_039081670.2 → XP_038937598.1  snurportin-1 isoform X9

      Conserved Domains (2) summary
      cd09232
      Location:98 → 202
      Snurportin-1_C; C-terminal m3G cap-binding domain of nuclear import adaptor snurportin-1
      pfam11538
      Location:25 → 64
      Snurportin1

    5. XM_063265673.1 → XP_063121743.1  snurportin-1 isoform X10

      UniProtKB/TrEMBL
      A6J4S1

    6. XM_006243124.2 → XP_006243186.1  snurportin-1 isoform X3

      Related
      ENSRNOP00000103426.1, ENSRNOT00000129195.1
      Conserved Domains (2) summary
      cd09232
      Location:116 → 300
      Snurportin-1_C; C-terminal m3G cap-binding domain of nuclear import adaptor snurportin-1
      pfam11538
      Location:43 → 82
      Snurportin1

    7. XM_039081669.2 → XP_038937597.1  snurportin-1 isoform X7

      Conserved Domains (2) summary
      cd09232
      Location:116 → 220
      Snurportin-1_C; C-terminal m3G cap-binding domain of nuclear import adaptor snurportin-1
      pfam11538
      Location:43 → 82
      Snurportin1

    8. XM_063265666.1 → XP_063121736.1  snurportin-1 isoform X1

    9. XM_063265670.1 → XP_063121740.1  snurportin-1 isoform X2

      Related
      ENSRNOP00000099920.1, ENSRNOT00000132077.1

    10. XM_063265668.1 → XP_063121738.1  snurportin-1 isoform X2

    11. XM_006243128.5 → XP_006243190.1  snurportin-1 isoform X4

      Conserved Domains (2) summary
      cd09232
      Location:116 → 274
      Snurportin-1_C; C-terminal m3G cap-binding domain of nuclear import adaptor snurportin-1
      pfam11538
      Location:43 → 82
      Snurportin1; Snurportin1

    12. XM_039081666.2 → XP_038937594.1  snurportin-1 isoform X5

      Conserved Domains (2) summary
      cd09232
      Location:116 → 274
      Snurportin-1_C; C-terminal m3G cap-binding domain of nuclear import adaptor snurportin-1
      pfam11538
      Location:43 → 82
      Snurportin1

    13. XM_039081668.2 → XP_038937596.1  snurportin-1 isoform X6

      Conserved Domains (2) summary
      cd09232
      Location:116 → 220
      Snurportin-1_C; C-terminal m3G cap-binding domain of nuclear import adaptor snurportin-1
      pfam11538
      Location:43 → 82
      Snurportin1
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q68FP5.1 GenPept UniProtKB/Swiss-Prot:Q68FP5

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