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    Fam91a1 family with sequence similarity 91, member A1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 689997, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fam91a1provided by RGD
    Official Full Name
    family with sequence similarity 91, member A1provided by RGD
    Primary source
    RGD:1586304
    See related
    EnsemblRapid:ENSRNOG00000008271 AllianceGenome:RGD:1586304
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in intracellular protein transport and vesicle tethering to Golgi. Predicted to be active in cytoplasmic vesicle and trans-Golgi network. Orthologous to human FAM91A1 (family with sequence similarity 91 member A1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 367.1), Liver (RPKM 277.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Fam91a1 in Genome Data Viewer
    Location:
    7q33
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (91857261..91897019)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (89969558..90007546)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (98302803..98341201)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene kelch-like family member 38 Neighboring gene uncharacterized LOC134479910 Neighboring gene annexin A13 Neighboring gene uncharacterized LOC134479911 Neighboring gene zinc finger CCHC-type containing 9, pseudogene 2 Neighboring gene uncharacterized LOC120093660 Neighboring gene fer-1-like family member 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The WDR11 complex facilitates the tethering of AP-1-derived vesicles. Navarro Negredo P, et al. Nat Commun, 2018 Feb 9. PMID 29426865, Free PMC Article
    2. TBC1D23 is a bridging factor for endosomal vesicle capture by golgins at the trans-Golgi. Shin JJH, et al. Nat Cell Biol, 2017 Dec. PMID 29084197, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC188756

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular protein transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in vesicle tethering to Golgi IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in vesicle tethering to Golgi ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasmic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasmic vesicle ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in trans-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in trans-Golgi network ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM91A1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001127578.1 → NP_001121050.1  protein FAM91A1

      See identical proteins and their annotated locations for NP_001121050.1

      Status: PROVISIONAL

      Source sequence(s)
      BC166852
      UniProtKB/TrEMBL
      A6HRK4, B2RYP3, F1LSP5
      Related
      ENSRNOP00000011797.6, ENSRNOT00000011797.9
      Conserved Domains (2) summary
      pfam14647
      Location:10 → 312
      FAM91_N; FAM91 N-terminus
      pfam14648
      Location:374 → 821
      FAM91_C; FAM91 C-terminus

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      91857261..91897019
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006241684.5 → XP_006241746.1  protein FAM91A1 isoform X1

      UniProtKB/TrEMBL
      A0A8I6GDV8, A6HRK4
      Related
      ENSRNOP00000086281.1, ENSRNOT00000113149.2
      Conserved Domains (2) summary
      pfam14647
      Location:10 → 312
      FAM91_N; FAM91 N-terminus
      pfam14648
      Location:374 → 757
      FAM91_C; FAM91 C-terminus

    RNA

    1. XR_001838719.3 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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