Slc25a31 solute carrier family 25 member 31 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slc25a31provided by RGD
Official Full Name: solute carrier family 25 member 31provided by RGD
Primary source: RGD:1596195
See related: EnsemblRapid:ENSRNOG00000038398 AllianceGenome:RGD:1596195
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable ATP:ADP antiporter activity. Predicted to be involved in male meiosis I; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; and spermatogenesis. Predicted to be located in membrane and mitochondrion. Predicted to be part of mitochondrial permeability transition pore complex. Orthologous to human SLC25A31 (solute carrier family 25 member 31). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 90.7) See more
Orthologs: human mouse all
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Genomic context

Location:: 2q26

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (125623331..125639155)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (123695387..123711275)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (127538323..127554276)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ATP:ADP antiporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in male meiosis I	ISO Inferred from Sequence Orthology more info
involved_in mitochondrial ADP transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial ATP transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of mitochondrial membrane permeability	ISO Inferred from Sequence Orthology more info
involved_in spermatogenesis	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
part_of mitochondrial permeability transition pore complex	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: ADP/ATP translocase 4; solute carrier family 25 member 31

Names: adenine nucleotide translocator), member 31; adenine nucleotide translocator), member 31-like; solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 31-like; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001433256.1 → NP_001420185.1 solute carrier family 25 member 31

Status: VALIDATED

Source sequence(s)

JAXUCZ010000002

UniProtKB/TrEMBL

D3ZB81

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086020.1 Reference GRCr8

Range

125623331..125639155

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039103630.2 → XP_038959558.1 ADP/ATP translocase 4

Related

ENSRNOP00000109304.1, ENSRNOT00000152689.1

Conserved Domains (1) summary

PTZ00169
Location:20 → 309

PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional