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    LINC02449 long intergenic non-protein coding RNA 2449 [ Homo sapiens (human) ]

    Gene ID: 101927905, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC02449provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 2449provided by HGNC
    Primary source
    HGNC:HGNC:53381
    See related
    Ensembl:ENSG00000215241 AllianceGenome:HGNC:53381
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Ubiquitous expression in thyroid (RPKM 2.5), brain (RPKM 2.4) and 25 other tissues See more
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    Genomic context

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    See LINC02449 in Genome Data Viewer
    Location:
    12p13.31
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (8235415..8242564)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (8249487..8256637)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (8388011..8395160)

    Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr12:8375857-8377056 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5931 Neighboring gene family with sequence similarity 90 member A1 Neighboring gene ALG1 like 10, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:8390159-8390659 Neighboring gene family with sequence similarity 86, member A pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4209 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4210 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4211 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4212 Neighboring gene uncharacterized LOC112268090 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4213 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:8396767-8397266 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:8404422-8404982 Neighboring gene ectonucleotide pyrophosphatase/phosphodiesterase 7 pseudogene 5 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:8432901-8433710 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr12:8437184-8438383 Neighboring gene uncharacterized LOC107987171 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5932 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr12:8472091-8472950

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Clone Names

    • DKFZp434B192

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_120454.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript.
      Source sequence(s)
      AC092111

    2. NR_120455.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an exon and its 3' terminal exon extends past a splice site used in in variant 1, resulting in a shorter transcript.
      Source sequence(s)
      AC092111
      Related
      ENST00000304751.9

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

      Range
      8235415..8242564
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060936.1 Alternate T2T-CHM13v2.0

      Range
      8249487..8256637
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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