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    galS DNA-binding transcriptional dual regulator GalS [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 949043, updated on 3-Dec-2024

    Summary

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    Official Symbol
    galS
    Official Full Name
    DNA-binding transcriptional dual regulator GalS
    Primary source
    ECOCYC:EG10365
    Locus tag
    b2151
    See related
    ASAP:ABE-0007110
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2144; mglD
    Summary
    The "Galactose isorepressor," GalS, is a DNA-binding transcription factor that represses transcription of the operons involved in transport and catabolism of D-galactose . [More information is available at EcoCyc: EG10365].
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    Genomic context

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    Sequence:
    NC_000913.3 (2240628..2241668, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene D-galactose/methyl-galactoside ABC transporter ATP binding subunit Neighboring gene D-galactose/methyl-galactoside ABC transporter periplasmic binding protein Neighboring gene DUF418 domain-containing protein YeiB Neighboring gene GTP cyclohydrolase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Adaptive mgl-regulatory mutations and genetic diversity evolving in glucose-limited Escherichia coli populations. Notley-McRobb L, et al. Environ Microbiol, 1999 Feb. PMID 11207716
    2. Regulation of the Escherichia coli methylgalactoside transport system by gene mglD. Robbins AR. J Bacteriol, 1975 Jul. PMID 1095564, Free PMC Article
    3. Interpretations of five monoclonal immunoassays of lutropin and follitropin: effects of normalization with WHO standard. Vermes I, et al. Clin Chem, 1991 Mar. PMID 1900742
    4. Locations and orientations on the Escherichia coli physical map of the mgl operon and galS, a new locus for galactose ultrainduction. Weickert MJ, et al. J Bacteriol, 1991 Dec. PMID 1938936, Free PMC Article
    5. DNA recognition and the code. Müller-Hill B, et al. Nature, 1994 Jun 23. PMID 8208287

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on complete protein
      Title: Functional characterization of roles of GalR and GalS as regulators of the gal regulon.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA-binding transcriptional dual regulator GalS

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2240628..2241668 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416656.1 DNA-binding transcriptional dual regulator GalS [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416656.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A895NXH4
      Conserved Domains (1) summary
      PRK10401
      Location:1 → 346
      PRK10401; HTH-type transcriptional regulator GalS
    Nucleotide Protein
    Heading Accession and Version

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