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    csgF curli assembly component CsgF [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945622, updated on 3-Dec-2024

    Summary

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    Official Symbol
    csgF
    Official Full Name
    curli assembly component CsgF
    Primary source
    ECOCYC:G6544
    Locus tag
    b1038
    See related
    ASAP:ABE-0003519
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1024
    Summary
    Overexpression causes abnormal biofilm architecture. [More information is available at EcoGene: EG13412]. An insertion in the csgF gene abolishes the formation of curli, although csgA, which encodes one of the structural subunits of curli, continues to be expressed . [More information is available at EcoCyc: G6544].
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    Genomic context

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    Sequence:
    NC_000913.3 (1101711..1102127, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene inner membrane protein YcdZ Neighboring gene curli secretion channel Neighboring gene curli assembly component CsgE Neighboring gene DNA-binding transcriptional dual regulator CsgD

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Localized and efficient curli nucleation requires the chaperone-like amyloid assembly protein CsgF. Nenninger AA, et al. Proc Natl Acad Sci U S A, 2009 Jan 20. PMID 19131513, Free PMC Article
    2. Biofilm formation by and multicellular behavior of Escherichia coli O55:H7, an atypical enteropathogenic strain. Weiss-Muszkat M, et al. Appl Environ Microbiol, 2010 Mar. PMID 20080991, Free PMC Article
    3. Structural and functional characterization of the Curli adaptor protein CsgF. Schubeis T, et al. FEBS Lett, 2018 Mar. PMID 29427517
    4. Genomic SELEX search for target promoters under the control of the PhoQP-RstBA signal relay cascade. Ogasawara H, et al. J Bacteriol, 2007 Jul. PMID 17468243, Free PMC Article
    5. Fishing new proteins in the twilight zone of genomes: the test case of outer membrane proteins in Escherichia coli K12, Escherichia coli O157:H7, and other Gram-negative bacteria. Casadio R, et al. Protein Sci, 2003 Jun. PMID 12761386, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The csgFG and crl mutants were deficient in their biofilm formation capabilities and did not form a pellicle at the air-liquid interface.
      Title: Biofilm formation by and multicellular behavior of Escherichia coli O55:H7, an atypical enteropathogenic strain.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within curli assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within curli assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein secretion by the type VIII secretion system IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell outer membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cell outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of curli secretion complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    curli assembly component CsgF

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1101711..1102127 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415556.1 curli assembly component CsgF [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415556.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5B9AJN7
      Conserved Domains (1) summary
      PRK10050
      Location:1 → 138
      PRK10050; curli production assembly/transport protein CsgF
    Nucleotide Protein
    Heading Accession and Version

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