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    hisM lysine/arginine/ornithine ABC transporter/histidine ABC transporter, membrane subunit HisM [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946790, updated on 3-Dec-2024

    Summary

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    Official Symbol
    hisM
    Official Full Name
    lysine/arginine/ornithine ABC transporter/histidine ABC transporter, membrane subunit HisM
    Primary source
    ECOCYC:EG10007
    Locus tag
    b2307
    See related
    ASAP:ABE-0007613
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2301
    Summary
    HisPMQJ is an ATP-dependent histidine transport system that is a member of the ATP-Binding Cassette (ABC) Superfamily of transporters . [More information is available at EcoCyc: EG10007].
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    Genomic context

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    Sequence:
    NC_000913.3 (2424517..2425233, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene recombination-promoting nuclease RpnB Neighboring gene lysine/arginine/ornithine ABC transporter/histidine ABC transporter, ATP binding subunit Neighboring gene lysine/arginine/ornithine ABC transporter/histidine ABC transporter, membrane subunit HisQ Neighboring gene histidine ABC transporter periplasmic binding protein Neighboring gene lysine/arginine/ornithine ABC transporter periplasmic binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A chimeric nucleotide-binding protein, encoded by a hisP-malK hybrid gene, is functional in maltose transport in Salmonella typhimurium. Schneider E, et al. Mol Microbiol, 1991 Jun. PMID 1787792
    2. Sequence of the complete P protein gene and part of the M protein gene from the histidine transport operon of Escherichia coli compared to that of Salmonella typhimurium. Kraft R, et al. Nucleic Acids Res, 1987 Oct 26. PMID 3313284, Free PMC Article
    3. Reconstitution of a bacterial periplasmic permease in proteoliposomes and demonstration of ATP hydrolysis concomitant with transport. Bishop L, et al. Proc Natl Acad Sci U S A, 1989 Sep. PMID 2674940, Free PMC Article
    4. Two periplasmic transport proteins which interact with a common membrane receptor show extensive homology: complete nucleotide sequences. Higgins CF, et al. Proc Natl Acad Sci U S A, 1981 Oct. PMID 6273842, Free PMC Article
    5. Characterization of transport through the periplasmic histidine permease using proteoliposomes reconstituted by dialysis. Liu CE, et al. J Biol Chem, 1997 Jan 10. PMID 8995374

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-histidine import across plasma membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in amino acid import across plasma membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in amino acid transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ATP-binding cassette (ABC) transporter complex RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lysine/arginine/ornithine ABC transporter/histidine ABC transporter, membrane subunit HisM
    NP_416810.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2424517..2425233 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416810.1 lysine/arginine/ornithine ABC transporter/histidine ABC transporter, membrane subunit HisM [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416810.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A377DPB0
      Conserved Domains (1) summary
      PRK15069
      Location:1 → 234
      PRK15069; histidine ABC transporter permease HisM
    Nucleotide Protein
    Heading Accession and Version

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