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    yehW glycine betaine ABC transporter membrane subunit YehW [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 949028, updated on 17-Dec-2024

    Summary

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    Official Symbol
    yehW
    Official Full Name
    glycine betaine ABC transporter membrane subunit YehW
    Primary source
    ECOCYC:EG12009
    Locus tag
    b2128
    See related
    ASAP:ABE-0007032
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2121
    Summary
    RpoS regulon. [More information is available at EcoGene: EG12009]. YehW is a membrane component of an ABC transporter involved in osmoprotection. [More information is available at EcoCyc: EG12009].
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    Genomic context

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    Sequence:
    NC_000913.3 (2215745..2216476, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional dual regulator BtsR Neighboring gene high-affinity pyruvate receptor Neighboring gene DNA-binding transcriptional activator MlrA Neighboring gene UPF0387 family protein YohO Neighboring gene glycine betaine ABC transporter ATP binding subunit YehX Neighboring gene glycine betaine ABC transporter membrane subunit YehY Neighboring gene glycine betaine ABC transporter periplasmic binding protein OsmF

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Osmoregulatory systems of Escherichia coli: identification of betaine-carnitine-choline transporter family member BetU and distributions of betU and trkG among pathogenic and nonpathogenic isolates. Ly A, et al. J Bacteriol, 2004 Jan. PMID 14702297, Free PMC Article
    2. YehZYXW of Escherichia coli Is a Low-Affinity, Non-Osmoregulatory Betaine-Specific ABC Transporter. Lang S, et al. Biochemistry, 2015 Sep 22. PMID 26325238
    3. Getting in or out: early segregation between importers and exporters in the evolution of ATP-binding cassette (ABC) transporters. Saurin W, et al. J Mol Evol, 1999 Jan. PMID 9873074
    4. Experimentally constrained topology models for 51,208 bacterial inner membrane proteins. Granseth E, et al. J Mol Biol, 2005 Sep 23. PMID 16120447
    5. Global topology analysis of the Escherichia coli inner membrane proteome. Daley DO, et al. Science, 2005 May 27. PMID 15919996

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in amino-acid betaine transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within glycine betaine transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glycine betaine ABC transporter membrane subunit YehW

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2215745..2216476 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416632.1 glycine betaine ABC transporter membrane subunit YehW [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416632.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6M9X4J5
      Conserved Domains (1) summary
      COG1174
      Location:23 → 239
      OpuBB; ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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