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    ampE protein AmpE [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946678, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ampE
    Official Full Name
    protein AmpE
    Primary source
    ECOCYC:EG10042
    Locus tag
    b0111
    See related
    ASAP:ABE-0000382
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0110
    Summary
    ampE encodes a cytoplasmic membrane protein believed to be involved in sensory transduction targeted to reduce expression of the -lactamase producing ampC gene through the AmpR regulator, which Escherichia coli does not posses . [More information is available at EcoCyc: EG10042].
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    Genomic context

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    Sequence:
    NC_000913.3 (119281..120135)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene prepilin-type N-terminal cleavage/methylation domain-containing protein PpdD Neighboring gene quinolinate phosphoribosyltransferase (decarboxylating) Neighboring gene 1,6-anhydro-N-acetylmuramoyl-L-alanine amidase Neighboring gene aromatic amino acid:H(+) symporter AroP Neighboring gene DNA-binding transcriptional dual regulator PdhR

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular basis of beta-lactamase induction in bacteria. Bennett PM, et al. Antimicrob Agents Chemother, 1993 Feb. PMID 8452343, Free PMC Article
    2. Regulation of enterobacterial cephalosporinase production: the role of a membrane-bound sensory transducer. Honoré N, et al. Mol Microbiol, 1989 Aug. PMID 2607970
    3. Signalling proteins in enterobacterial AmpC beta-lactamase regulation. Lindquist S, et al. Mol Microbiol, 1989 Aug. PMID 2691840
    4. Experimentally constrained topology models for 51,208 bacterial inner membrane proteins. Granseth E, et al. J Mol Biol, 2005 Sep 23. PMID 16120447
    5. Global topology analysis of the Escherichia coli inner membrane proteome. Daley DO, et al. Science, 2005 May 27. PMID 15919996

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    involved_in response to antibiotic IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein AmpE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      119281..120135
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414653.1 protein AmpE [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414653.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8T6Q292, A0AAN5UCP0
      Conserved Domains (1) summary
      pfam17113
      Location:1 → 284
      AmpE; Regulatory signalling modulator protein AmpE
    Nucleotide Protein
    Heading Accession and Version

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