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    sanA DUF218 domain-containing protein SanA [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 949003, updated on 3-Dec-2024

    Summary

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    Official Symbol
    sanA
    Official Full Name
    DUF218 domain-containing protein SanA
    Primary source
    ECOCYC:EG12025
    Locus tag
    b2144
    See related
    ASAP:ABE-0007091
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2137; sfiXSt; yeiF
    Summary
    ydcF and ycbC (COG1434) and sanA and yjgQ (COG2949) are four members of the DUF218 superfamily (PF02698). [More information is available at EcoGene: EG12025]. sanA encodes an inner membrane protein which is likely to be involved in cell envelope barrier functions. [More information is available at EcoCyc: EG12025].
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    Genomic context

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    Sequence:
    NC_000913.3 (2232878..2233597)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative 3-hydroxypropanoate export protein YohJ Neighboring gene putative 3-hydroxypropanoate export protein YohK Neighboring gene cytidine/deoxycytidine deaminase Neighboring gene DUF2542 domain-containing protein YeiS Neighboring gene dihydropyrimidine dehydrogenase (NAD(+)) subunit PreT Neighboring gene dihydropyrimidine dehydrogenase (NAD(+)) subunit PreA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel RpoS-Dependent Mechanisms Strengthen the Envelope Permeability Barrier during Stationary Phase. Mitchell AM, et al. J Bacteriol, 2017 Jan 15. PMID 27821607, Free PMC Article
    2. Cloning and nucleotide sequence of the Escherichia coli cytidine deaminase (ccd) gene. Yang C, et al. Biochemistry, 1992 May 5. PMID 1567863
    3. The Escherichia coli YdcF binds S-adenosyl-L-methionine and adopts an alpha/beta-fold characteristic of nucleotide-utilizing enzymes. Chao KL, et al. Proteins, 2008 Jul. PMID 18393394
    4. Genome-wide transcriptional analysis of the cold shock response in wild-type and cold-sensitive, quadruple-csp-deletion strains of Escherichia coli. Phadtare S, et al. J Bacteriol, 2004 Oct. PMID 15466053, Free PMC Article
    5. Membranome: a database for proteome-wide analysis of single-pass membrane proteins. Lomize AL, et al. Nucleic Acids Res, 2017 Jan 4. PMID 27510400, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    acts_upstream_of_or_within response to carbon starvation EXP
    Inferred from Experiment
    more info
    		 PubMed 
    acts_upstream_of_or_within response to xenobiotic stimulus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in outer membrane-bounded periplasmic space RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DUF218 domain-containing protein SanA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2232878..2233597
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416649.1 DUF218 domain-containing protein SanA [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416649.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5B9AHM1, W1F392
      Conserved Domains (1) summary
      PRK10834
      Location:1 → 239
      PRK10834; outer membrane permeability protein SanA
    Nucleotide Protein
    Heading Accession and Version

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