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    rplS 50S ribosomal subunit protein L19 [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947096, updated on 3-Dec-2024

    Summary

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    Official Symbol
    rplS
    Official Full Name
    50S ribosomal subunit protein L19
    Primary source
    ECOCYC:EG10880
    Locus tag
    b2606
    See related
    ASAP:ABE-0008574
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2603
    Summary
    The L19 protein is a component of the 50S subunit of the ribosome. [More information is available at EcoCyc: EG10880].
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    Genomic context

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    Sequence:
    NC_000913.3 (2744183..2744530, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF4154 domain-containing protein YfiR Neighboring gene diguanylate cyclase DgcN Neighboring gene lipoprotein YfiB Neighboring gene tRNA m(1)G37 methyltransferase Neighboring gene ribosome maturation factor RimM

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Alterations in ribosomal protein L19 that decrease the fidelity of translation. VanNice J, et al. Biochimie, 2016 Sep-Oct. PMID 27477481, Free PMC Article
    2. Primary structure of protein L19 from the large subunit of Escherichia coli ribosomes. Brosius J, et al. Biochemistry, 1978 Feb 7. PMID 339951
    3. Proteins associated with rRNA in the Escherichia coli ribosome. Bernabeu C, et al. Biochim Biophys Acta, 1978 Apr 27. PMID 350280
    4. Non-autogenous control of ribosomal protein synthesis from the trmD operon in Escherichia coli. Wikström PM, et al. J Mol Biol, 1988 Sep 5. PMID 2460631
    5. Reversion from erythromycin dependence in Escherichia coli: strains altered in ribosomal sub-unit association and ribosome assembly. Wild DG. J Gen Microbiol, 1988 May. PMID 2462010

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data show that ribosomal protein L19 (rplS) mutants promote increased stop codon readthrough, but do not have major effects on subunit association or cell growth.
      Title: Alterations in ribosomal protein L19 that decrease the fidelity of translation.
    2. N-terminus verified by Edman degradation on mature peptide
      Title: Primary structure of protein L19 from the large subunit of Escherichia coli ribosomes.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables large ribosomal subunit rRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in ribosomal large subunit assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    50S ribosomal subunit protein L19

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2744183..2744530 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417097.1 50S ribosomal subunit protein L19 [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417097.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376Y497
      Conserved Domains (1) summary
      PRK05338
      Location:2 → 115
      rplS; 50S ribosomal protein L19; Provisional
    Nucleotide Protein
    Heading Accession and Version

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