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    speF inducible ornithine decarboxylase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945297, updated on 3-Dec-2024

    Summary

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    Official Symbol
    speF
    Official Full Name
    inducible ornithine decarboxylase
    Primary source
    ECOCYC:EG10964
    Locus tag
    b0693
    See related
    ASAP:ABE-0002362
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0681
    Summary
    Lack of cadBA opereon induction results in an increase in speF-potE operon expression. [More information is available at EcoGene: EG10964].
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    Genomic context

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    Sequence:
    NC_000913.3 (718262..720460, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene putrescine transporter PotE Neighboring gene leader peptide SpeFL Neighboring gene DNA-binding transcriptional activator KdpE Neighboring gene sensor histidine kinase KdpD

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The enzymatic activities of the Escherichia coli basic aliphatic amino acid decarboxylases exhibit a pH zone of inhibition. Kanjee U, et al. Biochemistry, 2011 Nov 1. PMID 21957966
    2. Biodegradative ornithine decarboxylase of Escherichia coli. Purification, properties, and pyridoxal 5'-phosphate binding site. Applebaum D, et al. Biochemistry, 1975 Aug 12. PMID 240388
    3. Involvement of ribonuclease III in the enhancement of expression of the speF-potE operon encoding inducible ornithine decarboxylase and polyamine transport protein. Kashiwagi K, et al. Biochem Biophys Res Commun, 1994 Apr 15. PMID 8166735
    4. Polyamines in microorganisms. Tabor CW, et al. Microbiol Rev, 1985 Mar. PMID 3157043, Free PMC Article
    5. Coexistence of the genes for putrescine transport protein and ornithine decarboxylase at 16 min on Escherichia coli chromosome. Kashiwagi K, et al. J Biol Chem, 1991 Nov 5. PMID 1939141

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables carboxy-lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ornithine decarboxylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ornithine decarboxylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ornithine decarboxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables pyridoxal phosphate binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in amino acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cellular response to acidic pH IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in putrescine biosynthetic process from ornithine IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in spermidine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    inducible ornithine decarboxylase
    NP_415220.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      718262..720460 complement
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415220.1 inducible ornithine decarboxylase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415220.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6M9WXX3
      Conserved Domains (1) summary
      PRK13578
      Location:1 → 719
      PRK13578; ornithine decarboxylase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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