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    glxK glycerate 2-kinase 2 [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945129, updated on 3-Dec-2024

    Summary

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    Official Symbol
    glxK
    Official Full Name
    glycerate 2-kinase 2
    Primary source
    ECOCYC:G6283
    Locus tag
    b0514
    See related
    ASAP:ABE-0001773
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0507; glxB5; ybbZ
    Summary
    Glycerate kinase II (GKII), encoded by glxK, catalyzes the formation of 3-phosphoglycerate from D-glycerate . [More information is available at EcoCyc: G6283].
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    Genomic context

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    Sequence:
    NC_000913.3 (541888..543033)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene allantoinase Neighboring gene putative purine transporter Neighboring gene (S)-ureidoglycine aminohydrolase Neighboring gene allantoate amidohydrolase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Only plant-type (GLYK) glycerate kinases produce d-glycerate 3-phosphate. Bartsch O, et al. FEBS Lett, 2008 Sep 3. PMID 18675808
    2. Purification and properties of D-glycerate 3-kinase from Escherichia coli. Doughty CC, et al. J Biol Chem, 1966 Feb 10. PMID 5325263
    3. An in vivo metabolic approach for deciphering the product specificity of glycerate kinase proves that both E. coli's glycerate kinases generate 2-phosphoglycerate. Zelcbuch L, et al. PLoS One, 2015. PMID 25823014, Free PMC Article
    4. Two forms of D-glycerate kinase in Escherichia coli. Ornston MK, et al. J Bacteriol, 1969 Mar. PMID 4887503, Free PMC Article
    5. A comprehensive library of fluorescent transcriptional reporters for Escherichia coli. Zaslaver A, et al. Nat Methods, 2006 Aug. PMID 16862137

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycerate 2-kinase activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables glycerate 2-kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glycerate 2-kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glycerate kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glycolate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within glycolate catabolic process IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within glyoxylate catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in organic acid phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glycerate 2-kinase 2
    NP_415047.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      541888..543033
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415047.1 glycerate 2-kinase 2 [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415047.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FRG5
      Conserved Domains (1) summary
      PRK09932
      Location:1 → 381
      PRK09932; glycerate 3-kinase
    Nucleotide Protein
    Heading Accession and Version

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