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    hdeD acid-resistance membrane protein [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948024, updated on 3-Dec-2024

    Summary

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    Official Symbol
    hdeD
    Official Full Name
    acid-resistance membrane protein
    Primary source
    ECOCYC:EG11495
    Locus tag
    b3511
    See related
    ASAP:ABE-0011467
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3495; yhiA
    Summary
    EvgAS regulon. [More information is available at EcoGene: EG11495]. HdeD is required for the acid resistance phenotype exhibited upon overproduction of YdeO . [More information is available at EcoCyc: EG11495].
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    Genomic context

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    Sequence:
    NC_000913.3 (3656995..3657567)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene periplasmic acid stress chaperone HdeB Neighboring gene periplasmic acid stress chaperone HdeA Neighboring gene ncRNA Neighboring gene DNA-binding transcriptional activator GadE

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Contrasting silencing mechanisms of the same target mRNA by two regulatory RNAs in Escherichia coli. Lalaouna D, et al. Nucleic Acids Res, 2018 Mar 16. PMID 29294085, Free PMC Article
    2. GadE (YhiE): a novel activator involved in the response to acid environment in Escherichia coli. Hommais F, et al. Microbiology (Reading), 2004 Jan. PMID 14702398
    3. Physical map location of a set of Escherichia coli genes (hde) whose expression is affected by the nucleoid protein H-NS. Yoshida T, et al. J Bacteriol, 1993 Dec. PMID 8244952, Free PMC Article
    4. Products of the Escherichia coli acid fitness island attenuate metabolite stress at extremely low pH and mediate a cell density-dependent acid resistance. Mates AK, et al. J Bacteriol, 2007 Apr. PMID 17259322, Free PMC Article
    5. Anticipating an alkaline stress through the Tor phosphorelay system in Escherichia coli. Bordi C, et al. Mol Microbiol, 2003 Apr. PMID 12657056

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Both CyaR and RprA can block the translation initiation of hdeD but only CyaR induces mRNA decay.
      Title: Contrasting silencing mechanisms of the same target mRNA by two regulatory RNAs in Escherichia coli.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    acts_upstream_of_or_within response to pH IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    acid-resistance membrane protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3656995..3657567
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417968.1 acid-resistance membrane protein [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417968.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0AAI9MER3
      Conserved Domains (1) summary
      PRK10209
      Location:1 → 190
      PRK10209; HdeD family acid-resistance protein
    Nucleotide Protein
    Heading Accession and Version

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