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    Cog8 component of oligomeric golgi complex 8 [ Mus musculus (house mouse) ]

    Gene ID: 97484, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cog8provided by MGI
    Official Full Name
    component of oligomeric golgi complex 8provided by MGI
    Primary source
    MGI:MGI:2142885
    See related
    Ensembl:ENSMUSG00000031916 AllianceGenome:MGI:2142885
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be involved in Golgi organization; glycosylation; and retrograde transport, vesicle recycling within Golgi. Predicted to be located in Golgi apparatus. Predicted to be part of Golgi transport complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIh. Orthologous to human COG8 (component of oligomeric golgi complex 8). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 33.4), adrenal adult (RPKM 23.1) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Cog8 in Genome Data Viewer
    Location:
    8 D3; 8 53.55 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (107775341..107783369, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (107048709..107056737, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene vacuolar protein sorting 4A Neighboring gene translocase of inner mitochondrial membrane 23 homolog pseudogene Neighboring gene peptide deformylase (mitochondrial) Neighboring gene STARR-positive B cell enhancer ABC_E3804 Neighboring gene NIP7, nucleolar pre-rRNA processing protein Neighboring gene transmembrane p24 trafficking protein 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in Golgi organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in Golgi organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in glycosylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in glycosylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in intra-Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in retrograde transport, vesicle recycling within Golgi IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in retrograde transport, vesicle recycling within Golgi ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of Golgi transport complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of Golgi transport complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of Golgi transport complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    conserved oligomeric Golgi complex subunit 8
    Names
    COG complex subunit 8
    conserved oligomeric Golgi complex protein 8

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_139229.4NP_631975.3  conserved oligomeric Golgi complex subunit 8

      See identical proteins and their annotated locations for NP_631975.3

      Status: VALIDATED

      Source sequence(s)
      AI426017, AK145515, CA324258
      Consensus CDS
      CCDS22643.1
      UniProtKB/Swiss-Prot
      Q8BFW5, Q9JJA2
      UniProtKB/TrEMBL
      Q3U5F9
      Related
      ENSMUSP00000093173.6, ENSMUST00000095517.12
      Conserved Domains (1) summary
      pfam04124
      Location:56394
      Dor1; Dor1-like family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      107775341..107783369 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)