gcsha glycine cleavage system protein H (aminomethyl carrier), a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gcshaprovided by ZNC
Official Full Name: glycine cleavage system protein H (aminomethyl carrier), aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050320-18
See related: Ensembl:ENSDARG00000091655 AllianceGenome:ZFIN:ZDB-GENE-050320-18
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fb14d10; wu:fw84b08; zgc:112535
Summary: Predicted to be involved in glycine decarboxylation via glycine cleavage system. Predicted to be part of glycine cleavage complex. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome. Orthologous to human GCSH (glycine cleavage system protein H). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 18

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (6145307..6151759, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (6004942..6011394, complement)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in glycine decarboxylation via glycine cleavage system	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within glycine decarboxylation via glycine cleavage system	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of glycine cleavage complex	IBA Inferred from Biological aspect of Ancestor more info
part_of glycine cleavage complex	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: glycine cleavage system protein H (aminomethyl carrier), a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.