gpr132b G protein-coupled receptor 132b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gpr132bprovided by ZNC
Official Full Name: G protein-coupled receptor 132bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040724-83
See related: Ensembl:ENSDARG00000103540 AllianceGenome:ZFIN:ZDB-GENE-040724-83
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:136260; si:ch211-20b12.2
Summary: Predicted to enable G protein-coupled receptor activity. Acts upstream of or within response to acidic pH. Predicted to be located in membrane. Is expressed in several structures, including digestive system; hematopoietic system; nervous system; pleuroperitoneal region; and scale. Orthologous to human GPR132 (G protein-coupled receptor 132). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 20

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (18345518..18351521, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (18445935..18451938, complement)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

GPR132 responds to a select panel of oxygenated polyunsaturated fatty acids to enhance both embryonic and adult hematopoiesis.
Title: Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in G1/S transition of mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of G2/M transition of mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within response to acidic pH	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: probable G-protein coupled receptor 132b

Names: G protein-coupled receptor -like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001025547.2 → NP_001020718.2 probable G-protein coupled receptor 132b

Status: VALIDATED

Source sequence(s)

CU861664, FQ377663

UniProtKB/TrEMBL

A0A0R4IEK2, A0A8M1N701

Related

ENSDARP00000133890.1, ENSDART00000158098.2

Conserved Domains (1) summary

pfam00001
Location:61 → 313

7tm_1; 7 transmembrane receptor (rhodopsin family)