pierce1 piercer of microtubule wall 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pierce1provided by ZNC
Official Full Name: piercer of microtubule wall 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-081104-197
See related: Ensembl:ENSDARG00000058940 AllianceGenome:ZFIN:ZDB-GENE-081104-197
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch211-248e11.2
Summary: Acts upstream of or within embryonic heart tube left/right pattern formation and outer dynein arm assembly. Predicted to be located in axonemal microtubule and nucleus. Is expressed in post-vent vasculature. Orthologous to human PIERCE1 (piercer of microtubule wall 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (11542852..11550276, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (11505147..11508470, complement)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within axoneme assembly	IEA Inferred from Electronic Annotation more info
involved_in axoneme assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in cilium movement	ISS Inferred from Sequence or Structural Similarity more info
involved_in determination of left/right symmetry	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within embryonic heart tube left/right pattern formation	IGI Inferred from Genetic Interaction more info	PubMed
involved_in establishment of left/right asymmetry	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within outer dynein arm assembly	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in axonemal microtubule	IEA Inferred from Electronic Annotation more info
located_in axonemal microtubule	ISS Inferred from Sequence or Structural Similarity more info
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: piercer of microtubule wall 2 protein

Names: UPF0691 protein C9orf116 homolog; ci116

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.