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    map7d1a MAP7 domain containing 1a [ Danio rerio (zebrafish) ]

    Gene ID: 565172, updated on 4-Jan-2025

    Summary

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    Official Symbol
    map7d1aprovided by ZNC
    Official Full Name
    MAP7 domain containing 1aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060503-22
    See related
    Ensembl:ENSDARG00000098802 AllianceGenome:ZFIN:ZDB-GENE-060503-22
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-207m11.1
    Summary
    Predicted to act upstream of or within microtubule cytoskeleton organization. Predicted to be located in microtubule cytoskeleton. Is expressed in ciliary marginal zone. Orthologous to human MAP7D1 (MAP7 domain containing 1). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See map7d1a in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (35661726..35773210)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (35708851..35820335)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene si:ch211-1i11.3 Neighboring gene uncharacterized LOC137487937 Neighboring gene uncharacterized LOC137487848 Neighboring gene uncharacterized LOC137487938

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Disruption of MAP7D1 Gene Function Increases the Risk of Doxorubicin-Induced Cardiomyopathy and Heart Failure. Li LP, et al. Biomed Res Int, 2021. PMID 34327238, Free PMC Article
    2. Forward Genetic Screening Using Behavioral Tests in Zebrafish: A Proof of Concept Analysis of Mutants. Gerlai R, et al. Behav Genet, 2017 Jan. PMID 27704300
    3. Reverse genetic analysis of neurogenesis in the zebrafish retina. Pujic Z, et al. Dev Biol, 2006 May 15. PMID 16603149
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Disruption of MAP7D1 Gene Function Increases the Risk of Doxorubicin-Induced Cardiomyopathy and Heart Failure.
      Title: Disruption of MAP7D1 Gene Function Increases the Risk of Doxorubicin-Induced Cardiomyopathy and Heart Failure.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within microtubule cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in microtubule cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    MAP7 domain-containing protein 1a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001326399.1 → NP_001313328.1  MAP7 domain-containing protein 1a

      Status: VALIDATED

      Source sequence(s)
      AL773558, FQ377622
      UniProtKB/TrEMBL
      A0A0R4IEP5, A0A8M1P8Y2
      Related
      ENSDARP00000132764.1, ENSDART00000161393.2
      Conserved Domains (3) summary
      pfam05672
      Location:499 → 659
      MAP7; MAP7 (E-MAP-115) family
      cd16269
      Location:166 → 178
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:95 → 192
      GBP_C; Guanylate-binding protein, C-terminal domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      35661726..35773210
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021466720.2 → XP_021322395.1  MAP7 domain-containing protein 1a isoform X2

      UniProtKB/TrEMBL
      A0A8M9PMI8
      Conserved Domains (3) summary
      pfam05672
      Location:513 → 673
      MAP7; MAP7 (E-MAP-115) family
      cl25602
      Location:92 → 179
      DUF3552; Domain of unknown function (DUF3552)
      cl26464
      Location:287 → 519
      Atrophin-1; Atrophin-1 family

    2. XM_068213984.1 → XP_068070085.1  MAP7 domain-containing protein 1a isoform X1

      UniProtKB/TrEMBL
      A0A8M9PD59

    3. XM_068213986.1 → XP_068070087.1  MAP7 domain-containing protein 1a isoform X4

      UniProtKB/TrEMBL
      A0A0R4IPE8, A0A8M3B1V8

    4. XM_068213987.1 → XP_068070088.1  MAP7 domain-containing protein 1a isoform X5

      UniProtKB/TrEMBL
      A0A8M9NZC0

    5. XM_068213990.1 → XP_068070091.1  MAP7 domain-containing protein 1a isoform X8

    6. XM_068213989.1 → XP_068070090.1  MAP7 domain-containing protein 1a isoform X7

      UniProtKB/TrEMBL
      A0A8M3AJC2

    7. XM_068213985.1 → XP_068070086.1  MAP7 domain-containing protein 1a isoform X3

      UniProtKB/TrEMBL
      A0A8M9PJJ8

    8. XM_068213988.1 → XP_068070089.1  MAP7 domain-containing protein 1a isoform X6

      UniProtKB/TrEMBL
      A0A8M9P7Z0

    9. XM_068213991.1 → XP_068070092.1  MAP7 domain-containing protein 1a isoform X9

      UniProtKB/TrEMBL
      A0A8M3ATP0
    Nucleotide Protein Strain
    Heading Accession and Version

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