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    htr5ab 5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate b [ Danio rerio (zebrafish) ]

    Gene ID: 368475, updated on 4-Jan-2025

    Summary

    Official Symbol
    htr5abprovided by ZNC
    Official Full Name
    5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030616-574
    See related
    Ensembl:ENSDARG00000068557 AllianceGenome:ZFIN:ZDB-GENE-030616-574
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    HTR5A; htr5al; si:zc12p8.3
    Summary
    Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger and chemical synaptic transmission. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in dendrite and plasma membrane. Orthologous to human HTR5A (5-hydroxytryptamine receptor 5A). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
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    Genomic context

    See htr5ab in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (41081853..41102498, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (40801780..40822425, complement)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene si:dkey-151p11.2 Neighboring gene insulin induced gene 1 Neighboring gene uncharacterized LOC137496190 Neighboring gene poly-U binding splicing factor b Neighboring gene scribble planar cell polarity protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables G protein-coupled serotonin receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables G protein-coupled serotonin receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables neurotransmitter receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate b
    Names
    5-hydroxytryptamine (serotonin) receptor 5A like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007121.2NP_001007122.1  5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate b

      See identical proteins and their annotated locations for NP_001007122.1

      Status: PROVISIONAL

      Source sequence(s)
      BC129143
      UniProtKB/TrEMBL
      A1L1N1, Q7ZZ32
      Related
      ENSDARP00000089964.2, ENSDART00000099192.4
      Conserved Domains (1) summary
      pfam00001
      Location:47327
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      41081853..41102498 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)