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    Mrps22 mitochondrial ribosomal protein S22 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 683519, updated on 9-Dec-2024

    Summary

    Official Symbol
    Mrps22provided by RGD
    Official Full Name
    mitochondrial ribosomal protein S22provided by RGD
    Primary source
    RGD:1585674
    See related
    EnsemblRapid:ENSRNOG00000047984 AllianceGenome:RGD:1585674
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial small ribosomal subunit. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 5 and ovarian dysgenesis 7. Orthologous to human MRPS22 (mitochondrial ribosomal protein S22). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 208.6), Muscle (RPKM 200.8) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Mrps22 in Genome Data Viewer
    Location:
    8q31
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (108063468..108076638, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (99184110..99197278, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (106604421..106617591, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene NME/NM23 nucleoside diphosphate kinase 2, pseudogene 8 Neighboring gene COPI coat complex subunit beta 2 Neighboring gene proline rich 23A, member 1 Neighboring gene proline rich 23A, member 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of mitochondrial small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of mitochondrial small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    small ribosomal subunit protein mS22
    Names
    28S ribosomal protein S22, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077530.1NP_001070998.1  small ribosomal subunit protein mS22

      See identical proteins and their annotated locations for NP_001070998.1

      Status: PROVISIONAL

      Source sequence(s)
      BC105629
      UniProtKB/TrEMBL
      A6I2B7, Q0D2L2
      Related
      ENSRNOP00000067192.1, ENSRNOT00000070953.4
      Conserved Domains (1) summary
      pfam10245
      Location:67307
      MRP-S22; Mitochondrial 28S ribosomal protein S22

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      108063468..108076638 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)