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    gluconokinase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851835, updated on 9-Dec-2024

    Summary

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    Official Full Name
    gluconokinase
    Primary source
    SGD:S000002656
    Locus tag
    YDR248C
    See related
    AllianceGenome:SGD:S000002656; FungiDB:YDR248C; VEuPathDB:YDR248C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables gluconokinase activity. Predicted to be involved in D-gluconate catabolic process. Located in fungal-type vacuole. Orthologous to human IDNK (IDNK gluconokinase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (957758..958339, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene putative serine/threonine protein kinase VHS1 Neighboring gene uncharacterized protein Neighboring gene Pam1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cellobionic acid utilization: from Neurospora crassa to Saccharomyces cerevisiae. Li X, et al. Biotechnol Biofuels, 2015. PMID 26279678, Free PMC Article
    2. A posttranscriptional role for the yeast Paf1-RNA polymerase II complex is revealed by identification of primary targets. Penheiter KL, et al. Mol Cell, 2005 Oct 28. PMID 16246724
    3. Assessing systems properties of yeast mitochondria through an interaction map of the organelle. Perocchi F, et al. PLoS Genet, 2006 Oct 20. PMID 17054397, Free PMC Article
    4. An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiae. Lesage G, et al. BMC Genet, 2005 Feb 16. PMID 15715908, Free PMC Article
    5. The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. Jacq C, et al. Nature, 1997 May 29. PMID 9169867

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables gluconokinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables gluconokinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables gluconokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in D-gluconate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in D-gluconate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in D-gluconate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in fungal-type vacuole HDA PubMed 

    General protein information

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    Preferred Names
    gluconokinase
    NP_010534.1
    • Putative gluconokinase; sequence similarity to bacterial and human gluconokinase; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; upregulated by deletion of the RNAP-II associated factor, PAF1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      957758..958339 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180556.1 → NP_010534.1  TPA: gluconokinase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010534.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VSM9, Q03786
      UniProtKB/TrEMBL
      A6ZYK1, B3LG40, B5VGD4, C7GTI4, C8Z5G0, G2WAZ2, N1P527
      Conserved Domains (1) summary
      TIGR01313
      Location:14 → 186
      therm_gnt_kin; carbohydrate kinase, thermoresistant glucokinase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03786.1

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