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    RPL31A ribosomal 60S subunit protein L31A [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851484, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RPL31A
    Official Full Name
    ribosomal 60S subunit protein L31A
    Primary source
    SGD:S000002233
    Locus tag
    YDL075W
    See related
    AllianceGenome:SGD:S000002233; FungiDB:YDL075W; VEuPathDB:YDL075W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RPL34
    Summary
    A structural constituent of ribosome. Involved in cytoplasmic translation and regulation of translational fidelity. Part of cytosolic large ribosomal subunit. Orthologous to human RPL31 (ribosomal protein L31). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RPL31A in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    2
    Sequence:
    Chromosome: IV; NC_001136.10 (322226..322988)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Vam6p Neighboring gene Rxt3p Neighboring gene ncRNA Neighboring gene E3 ubiquitin-protein ligase BRE1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The primary structure of a gene encoding yeast ribosomal protein L34. Schaap PJ, et al. Curr Genet, 1984 Dec. PMID 24173509
    2. Dual interaction of the Hsp70 J-protein cochaperone Zuotin with the 40S and 60S ribosomal subunits. Lee K, et al. Nat Struct Mol Biol, 2016 Nov. PMID 27669034, Free PMC Article
    3. Ribosome-associated complex binds to ribosomes in close proximity of Rpl31 at the exit of the polypeptide tunnel in yeast. Peisker K, et al. Mol Biol Cell, 2008 Dec. PMID 18829863, Free PMC Article
    4. A natural polymorphism in rDNA replication origins links origin activation with calorie restriction and lifespan. Kwan EX, et al. PLoS Genet, 2013. PMID 23505383, Free PMC Article
    5. Yeast Replicator: A High-Throughput Multiplexed Microfluidics Platform for Automated Measurements of Single-Cell Aging. Liu P, et al. Cell Rep, 2015 Oct 20. PMID 26456818, Free PMC Article

    See all (116) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cytoplasmic translation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of translational fidelity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 60S subunit protein L31A
    NP_010208.1
    • Ribosomal 60S subunit protein L31A; associates with karyopherin Sxm1p; loss of both Rpl31p and Rpl39p confers lethality; homologous to mammalian ribosomal protein L31, no bacterial homolog; RPL31A has a paralog, RPL31B, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      322226..322988
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180134.1 → NP_010208.1  TPA: ribosomal 60S subunit protein L31A [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010208.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VRS4, P04649, P0C2H8, Q3E7B8
      UniProtKB/TrEMBL
      A6ZXQ3, B3LGX0, C7GJN7, C8Z4J5, G2WC88, N1P462
      Conserved Domains (1) summary
      pfam01198
      Location:6 → 87
      Ribosomal_L31e; Ribosomal protein L31e
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0C2H8.1

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