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    Zfp612 zinc finger protein 612 [ Mus musculus (house mouse) ]

    Gene ID: 234725, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zfp612provided by MGI
    Official Full Name
    zinc finger protein 612provided by MGI
    Primary source
    MGI:MGI:2443465
    See related
    Ensembl:ENSMUSG00000044676 AllianceGenome:MGI:2443465
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    B230354B21Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in central nervous system; early conceptus; reproductive system; and urinary system. Orthologous to human ZNF23 (zinc finger protein 23). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in cerebellum adult (RPKM 8.9), cortex adult (RPKM 5.8) and 18 other tissues See more
    Orthologs
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    Genomic context

    See Zfp612 in Genome Data Viewer
    Location:
    8 D3; 8 57.41 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (110806331..110819385)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (110079705..110092753)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene carbohydrate sulfotransferase 4 Neighboring gene RIKEN cDNA 8030455M16 gene Neighboring gene TLE family member 7 Neighboring gene predicted gene, 35543

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175480.4NP_780689.3  zinc finger protein 23

      See identical proteins and their annotated locations for NP_780689.3

      Status: VALIDATED

      Source sequence(s)
      AC124409, AI603944, AK046220, AK162867, BY123080
      Consensus CDS
      CCDS22660.1
      UniProtKB/TrEMBL
      A0A1D5RMC2
      Related
      ENSMUSP00000148717.2, ENSMUST00000212754.2
      Conserved Domains (3) summary
      smart00349
      Location:1171
      KRAB; krueppel associated box
      COG5048
      Location:251657
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:451471
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      110806331..110819385
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006530908.2XP_006530971.1  zinc finger protein 23 isoform X1

      See identical proteins and their annotated locations for XP_006530971.1

      Conserved Domains (3) summary
      smart00349
      Location:74134
      KRAB; krueppel associated box
      COG5048
      Location:314720
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:514534
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. XM_006530910.4XP_006530973.1  zinc finger protein 23 isoform X3

      See identical proteins and their annotated locations for XP_006530973.1

      Conserved Domains (3) summary
      smart00349
      Location:2282
      KRAB; krueppel associated box
      COG5048
      Location:262668
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:462482
      ZF_C2H2; C2H2 Zn finger [structural motif]
    3. XM_006530912.4XP_006530975.1  zinc finger protein 23 isoform X4

      See identical proteins and their annotated locations for XP_006530975.1

      UniProtKB/TrEMBL
      A0A1D5RMC2
      Conserved Domains (3) summary
      smart00349
      Location:1171
      KRAB; krueppel associated box
      COG5048
      Location:251657
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:451471
      ZF_C2H2; C2H2 Zn finger [structural motif]
    4. XM_030243508.1XP_030099368.1  zinc finger protein 23 isoform X5

      Conserved Domains (3) summary
      COG5048
      Location:215621
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:415435
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:1050
      KRAB; KRAB box
    5. XM_006530907.4XP_006530970.1  zinc finger protein 23 isoform X1

      See identical proteins and their annotated locations for XP_006530970.1

      Conserved Domains (3) summary
      smart00349
      Location:74134
      KRAB; krueppel associated box
      COG5048
      Location:314720
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:514534
      ZF_C2H2; C2H2 Zn finger [structural motif]
    6. XM_011248359.3XP_011246661.1  zinc finger protein 23 isoform X2

      Conserved Domains (3) summary
      COG5048
      Location:278684
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:478498
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:73113
      KRAB; KRAB box
    7. XM_006530909.4XP_006530972.1  zinc finger protein 23 isoform X3

      See identical proteins and their annotated locations for XP_006530972.1

      Conserved Domains (3) summary
      smart00349
      Location:2282
      KRAB; krueppel associated box
      COG5048
      Location:262668
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:462482
      ZF_C2H2; C2H2 Zn finger [structural motif]
    8. XM_030243509.1XP_030099369.1  zinc finger protein 23 isoform X6

      UniProtKB/TrEMBL
      G5E8C8, Q3V041
      Conserved Domains (3) summary
      COG5048
      Location:212618
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:412432
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:132
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    9. XM_006530915.4XP_006530978.1  zinc finger protein 23 isoform X6

      See identical proteins and their annotated locations for XP_006530978.1

      UniProtKB/TrEMBL
      G5E8C8, Q3V041
      Related
      ENSMUSP00000062474.10, ENSMUST00000058804.10
      Conserved Domains (3) summary
      COG5048
      Location:212618
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:412432
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:132
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    10. XM_030243507.1XP_030099367.1  zinc finger protein 23 isoform X5

      Conserved Domains (3) summary
      COG5048
      Location:215621
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:415435
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:1050
      KRAB; KRAB box
    11. XM_011248360.2XP_011246662.1  zinc finger protein 23 isoform X6

      See identical proteins and their annotated locations for XP_011246662.1

      UniProtKB/TrEMBL
      G5E8C8, Q3V041
      Conserved Domains (3) summary
      COG5048
      Location:212618
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:412432
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:132
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box