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    Pkp4 plakophilin 4 [ Mus musculus (house mouse) ]

    Gene ID: 227937, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Pkp4provided by MGI
    Official Full Name
    plakophilin 4provided by MGI
    Primary source
    MGI:MGI:109281
    See related
    Ensembl:ENSMUSG00000026991 AllianceGenome:MGI:109281
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Armrp; p0071; 5031422I09Rik; 9430019K17Rik
    Summary
    Predicted to enable cadherin binding activity. Involved in cell-cell junction assembly. Located in postsynaptic density. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and respiratory system. Orthologous to human PKP4 (plakophilin 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in kidney adult (RPKM 42.6), cerebellum adult (RPKM 33.0) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Pkp4 in Genome Data Viewer
    Location:
    2 C1.1; 2 33.52 cM
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (58991123..59185549)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (59160850..59355205)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene uridine phosphorylase 2 Neighboring gene STARR-seq mESC enhancer starr_04557 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene coiled-coil domain containing 148 Neighboring gene STARR-seq mESC enhancer starr_04559 Neighboring gene STARR-seq mESC enhancer starr_04561 Neighboring gene predicted gene, 54155 Neighboring gene STARR-positive B cell enhancer mm9_chr2:58998596-58998897 Neighboring gene STARR-seq mESC enhancer starr_04563 Neighboring gene STARR-seq mESC enhancer starr_04569 Neighboring gene RIKEN cDNA 5330411J11 gene Neighboring gene STARR-seq mESC enhancer starr_04570 Neighboring gene STARR-seq mESC enhancer starr_04571 Neighboring gene STARR-seq mESC enhancer starr_04573 Neighboring gene predicted gene 13551

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Plakophilin 4 controls the spatio-temporal activity of RhoA at adherens junctions to promote cortical actin ring formation and tissue tension. Müller L, et al. Cell Mol Life Sci, 2024 Jul 6. PMID 38970683, Free PMC Article
    2. A feedback loop between plakophilin 4 and YAP signaling regulates keratinocyte differentiation. Müller L, et al. iScience, 2024 Sep 20. PMID 39286493, Free PMC Article
    3. FMRP regulates actin filament organization via the armadillo protein p0071. Nolze A, et al. RNA, 2013 Nov. PMID 24062571, Free PMC Article
    4. Cloning and characterization of a new armadillo family member, p0071, associated with the junctional plaque: evidence for a subfamily of closely related proteins. Hatzfeld M, et al. J Cell Sci, 1996 Nov. PMID 8937994
    5. ERBIN associates with p0071, an armadillo protein, at cell-cell junctions of epithelial cells. Izawa I, et al. Genes Cells, 2002 May. PMID 12047349

    See all (51) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Gene trapped (1)  1 citation
    • Targeted (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC100358, MGC105166

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cadherin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell-cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell-cell junction assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of GTPase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of cytokinesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of cytokinesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in adherens junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
    		  
    colocalizes_with cell-cell contact zone ISO
    Inferred from Sequence Orthology
    more info
    		  
    colocalizes_with cell-cell contact zone ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in cell-cell junction ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cell-cell junction ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in cytoplasmic side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasmic side of plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoskeleton ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in desmosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in desmosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    colocalizes_with midbody ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in midbody ISO
    Inferred from Sequence Orthology
    more info
    		  
    colocalizes_with midbody ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in midbody ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in mitotic spindle ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in mitotic spindle ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in perinuclear region of cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in postsynaptic density IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in spindle midzone ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in spindle midzone ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in spindle pole ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in spindle pole ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    plakophilin-4
    Names
    armadillo-related protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362990.1 → NP_001349919.1  plakophilin-4 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL845536, BX649232
      Conserved Domains (5) summary
      smart00185
      Location:862 → 897
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:845 → 966
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:527 → 552
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:556 → 595
      Arm; Armadillo/beta-catenin-like repeat
      pfam15449
      Location:74 → 338
      Retinal; Retinal protein

    2. NM_001362991.1 → NP_001349920.1  plakophilin-4 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL845536, BX649232
      Conserved Domains (4) summary
      smart00185
      Location:555 → 595
      ARM; Armadillo/beta-catenin-like repeats
      pfam05642
      Location:90 → 402
      Sporozoite_P67; Sporozoite P67 surface antigen
      sd00043
      Location:526 → 551
      ARM; armadillo repeat [structural motif]
      cl27106
      Location:844 → 965
      PLN03200; cellulose synthase-interactive protein; Provisional

    3. NM_001362992.1 → NP_001349921.1  plakophilin-4 isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5), as well as variants 6 and 7, encodes isoform 5.
      Source sequence(s)
      AL845536, BX649232
      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:716 → 751
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:699 → 820
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:381 → 406
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:410 → 449
      Arm; Armadillo/beta-catenin-like repeat

    4. NM_001362993.1 → NP_001349922.1  plakophilin-4 isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6), as well as variants 5 and 7, encodes isoform 5.
      Source sequence(s)
      AL845536, BX649232
      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:716 → 751
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:699 → 820
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:381 → 406
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:410 → 449
      Arm; Armadillo/beta-catenin-like repeat

    5. NM_001362994.1 → NP_001349923.1  plakophilin-4 isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7), as well as variants 5 and 6, encodes isoform 5.
      Source sequence(s)
      AL845536, BX649232
      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:716 → 751
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:699 → 820
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:381 → 406
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:410 → 449
      Arm; Armadillo/beta-catenin-like repeat

    6. NM_001362995.1 → NP_001349924.1  plakophilin-4 isoform 6

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8), as well as variant 9, encodes isoform 6.
      Source sequence(s)
      AL845536, BX649232
      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:715 → 750
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:698 → 819
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:380 → 405
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:409 → 448
      Arm; Armadillo/beta-catenin-like repeat

    7. NM_001362996.1 → NP_001349925.1  plakophilin-4 isoform 6

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9), as well as variant 8, encodes isoform 6.
      Source sequence(s)
      AL845536, BX649232
      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:715 → 750
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:698 → 819
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:380 → 405
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:409 → 448
      Arm; Armadillo/beta-catenin-like repeat

    8. NM_001362997.1 → NP_001349926.1  plakophilin-4 isoform 7

      Status: VALIDATED

      Description
      Transcript Variant: This variant (10), as well as variants 11 and 12, encodes isoform 7.
      Source sequence(s)
      AL845536, BX649232
      Consensus CDS
      CCDS89490.1
      UniProtKB/TrEMBL
      A2AS47
      Conserved Domains (4) summary
      smart00185
      Location:523 → 558
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:506 → 627
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:188 → 213
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:217 → 256
      Arm; Armadillo/beta-catenin-like repeat

    9. NM_001362998.1 → NP_001349927.1  plakophilin-4 isoform 7

      Status: VALIDATED

      Description
      Transcript Variant: This variant (11), as well as variants 10 and 12, encodes isoform 7.
      Source sequence(s)
      AL845536, BX649232
      Consensus CDS
      CCDS89490.1
      UniProtKB/TrEMBL
      A2AS47
      Conserved Domains (4) summary
      smart00185
      Location:523 → 558
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:506 → 627
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:188 → 213
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:217 → 256
      Arm; Armadillo/beta-catenin-like repeat

    10. NM_001362999.1 → NP_001349928.1  plakophilin-4 isoform 7

      Status: VALIDATED

      Description
      Transcript Variant: This variant (12), as well as variants 10 and 11, encodes isoform 7.
      Source sequence(s)
      AL845536, BX649232
      Consensus CDS
      CCDS89490.1
      UniProtKB/TrEMBL
      A2AS47
      Conserved Domains (4) summary
      smart00185
      Location:523 → 558
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:506 → 627
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:188 → 213
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:217 → 256
      Arm; Armadillo/beta-catenin-like repeat

    11. NM_026361.2 → NP_080637.1  plakophilin-4 isoform 1

      See identical proteins and their annotated locations for NP_080637.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) is the longer transcript and it encodes the longer protein (isoform 1).
      Source sequence(s)
      AA266974, AK146720, BC079848
      Consensus CDS
      CCDS16052.1
      UniProtKB/Swiss-Prot
      A2AS46, Q640N0, Q68FH0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3
      Related
      ENSMUSP00000099815.5, ENSMUST00000102754.11
      Conserved Domains (6) summary
      smart00185
      Location:864 → 899
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:847 → 968
      PLN03200; cellulose synthase-interactive protein; Provisional
      PRK14949
      Location:2 → 409
      PRK14949; DNA polymerase III subunits gamma and tau; Provisional
      sd00043
      Location:529 → 554
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:558 → 597
      Arm; Armadillo/beta-catenin-like repeat
      pfam15449
      Location:171 → 340
      Retinal; Retinal protein

    12. NM_175464.2 → NP_780673.2  plakophilin-4 isoform 2

      See identical proteins and their annotated locations for NP_780673.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame segment in the 3' coding region, compared to variant 1. The resulting protein (isoform 2) has a shorter C-terminus when it is compared to isoform 1.
      Source sequence(s)
      AA266974, AK146720, BC082578
      Consensus CDS
      CCDS50588.1
      UniProtKB/Swiss-Prot
      Q68FH0
      UniProtKB/TrEMBL
      Q3UIX3
      Related
      ENSMUSP00000129836.2, ENSMUST00000168631.8
      Conserved Domains (4) summary
      smart00185
      Location:948 → 992
      ARM; Armadillo/beta-catenin-like repeats
      cd00020
      Location:521 → 643
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam13646
      Location:529 → 632
      HEAT_2; HEAT repeats
      sd00043
      Location:529 → 554
      ARM; armadillo repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      58991123..59185549
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036160995.1 → XP_036016888.1  plakophilin-4 isoform X1

      Conserved Domains (5) summary
      smart00185
      Location:880 → 915
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:863 → 984
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:545 → 570
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:574 → 613
      Arm; Armadillo/beta-catenin-like repeat
      pfam03154
      Location:72 → 382
      Atrophin-1; Atrophin-1 family

    2. XM_036161000.1 → XP_036016893.1  plakophilin-4 isoform X2

      Conserved Domains (5) summary
      smart00185
      Location:879 → 914
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:862 → 983
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:544 → 569
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:573 → 612
      Arm; Armadillo/beta-catenin-like repeat
      pfam03154
      Location:72 → 382
      Atrophin-1; Atrophin-1 family

    3. XM_036161060.1 → XP_036016953.1  plakophilin-4 isoform X17

      Conserved Domains (5) summary
      smart00185
      Location:617 → 658
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:862 → 983
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:544 → 569
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:573 → 612
      Arm; Armadillo/beta-catenin-like repeat
      pfam03154
      Location:72 → 382
      Atrophin-1; Atrophin-1 family

    4. XM_006499172.4 → XP_006499235.1  plakophilin-4 isoform X5

      Conserved Domains (6) summary
      PLN03209
      Location:220 → 377
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:863 → 898
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:846 → 967
      PLN03200; cellulose synthase-interactive protein; Provisional
      PRK14949
      Location:2 → 409
      PRK14949; DNA polymerase III subunits gamma and tau; Provisional
      sd00043
      Location:528 → 553
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:557 → 596
      Arm; Armadillo/beta-catenin-like repeat

    5. XM_036161007.1 → XP_036016900.1  plakophilin-4 isoform X7

      UniProtKB/TrEMBL
      A2AS45
      Related
      ENSMUSP00000042249.9, ENSMUST00000037903.15
      Conserved Domains (5) summary
      smart00185
      Location:618 → 659
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:863 → 984
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:545 → 570
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:574 → 613
      Arm; Armadillo/beta-catenin-like repeat
      pfam03154
      Location:72 → 382
      Atrophin-1; Atrophin-1 family

    6. XM_036161009.1 → XP_036016902.1  plakophilin-4 isoform X8

      Conserved Domains (5) summary
      smart00185
      Location:880 → 915
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:863 → 984
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:545 → 570
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:574 → 613
      Arm; Armadillo/beta-catenin-like repeat
      pfam03154
      Location:72 → 382
      Atrophin-1; Atrophin-1 family

    7. XM_006499175.5 → XP_006499238.1  plakophilin-4 isoform X10

      Conserved Domains (6) summary
      smart00185
      Location:864 → 899
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:847 → 968
      PLN03200; cellulose synthase-interactive protein; Provisional
      PRK14949
      Location:2 → 409
      PRK14949; DNA polymerase III subunits gamma and tau; Provisional
      sd00043
      Location:529 → 554
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:558 → 597
      Arm; Armadillo/beta-catenin-like repeat
      pfam15449
      Location:171 → 340
      Retinal; Retinal protein

    8. XM_036161002.1 → XP_036016895.1  plakophilin-4 isoform X3

      Conserved Domains (5) summary
      smart00185
      Location:878 → 913
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:861 → 982
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:543 → 568
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:572 → 611
      Arm; Armadillo/beta-catenin-like repeat
      pfam03154
      Location:72 → 380
      Atrophin-1; Atrophin-1 family

    9. XM_030250162.1 → XP_030106022.1  plakophilin-4 isoform X15

      UniProtKB/TrEMBL
      A2AS47
      Conserved Domains (4) summary
      smart00185
      Location:523 → 558
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:506 → 627
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:188 → 213
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:217 → 256
      Arm; Armadillo/beta-catenin-like repeat

    10. XM_036161044.1 → XP_036016937.1  plakophilin-4 isoform X12

      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:715 → 750
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:698 → 819
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:380 → 405
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:409 → 448
      Arm; Armadillo/beta-catenin-like repeat

    11. XM_036161043.1 → XP_036016936.1  plakophilin-4 isoform X11

      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:716 → 751
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:699 → 820
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:381 → 406
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:410 → 449
      Arm; Armadillo/beta-catenin-like repeat

    12. XM_036161045.1 → XP_036016938.1  plakophilin-4 isoform X13

      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:716 → 751
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:699 → 820
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:381 → 406
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:410 → 449
      Arm; Armadillo/beta-catenin-like repeat

    13. XM_036161012.1 → XP_036016905.1  plakophilin-4 isoform X9

      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:732 → 767
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:715 → 836
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:397 → 422
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:426 → 465
      Arm; Armadillo/beta-catenin-like repeat

    14. XM_036161037.1 → XP_036016930.1  plakophilin-4 isoform X9

      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:732 → 767
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:715 → 836
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:397 → 422
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:426 → 465
      Arm; Armadillo/beta-catenin-like repeat

    15. XM_036161025.1 → XP_036016918.1  plakophilin-4 isoform X9

      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:732 → 767
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:715 → 836
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:397 → 422
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:426 → 465
      Arm; Armadillo/beta-catenin-like repeat

    16. XM_036161028.1 → XP_036016921.1  plakophilin-4 isoform X9

      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:732 → 767
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:715 → 836
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:397 → 422
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:426 → 465
      Arm; Armadillo/beta-catenin-like repeat

    17. XM_036161050.1 → XP_036016943.1  plakophilin-4 isoform X14

      Conserved Domains (4) summary
      smart00185
      Location:539 → 574
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:522 → 643
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:204 → 229
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:233 → 272
      Arm; Armadillo/beta-catenin-like repeat

    18. XM_036161036.1 → XP_036016929.1  plakophilin-4 isoform X9

      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:732 → 767
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:715 → 836
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:397 → 422
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:426 → 465
      Arm; Armadillo/beta-catenin-like repeat

    19. XM_036161039.1 → XP_036016932.1  plakophilin-4 isoform X9

      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:732 → 767
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:715 → 836
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:397 → 422
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:426 → 465
      Arm; Armadillo/beta-catenin-like repeat

    20. XM_036161004.1 → XP_036016897.1  plakophilin-4 isoform X4

      Conserved Domains (5) summary
      smart00185
      Location:877 → 912
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:860 → 981
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:542 → 567
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:571 → 610
      Arm; Armadillo/beta-catenin-like repeat
      pfam03154
      Location:72 → 380
      Atrophin-1; Atrophin-1 family

    21. XM_036161046.1 → XP_036016939.1  plakophilin-4 isoform X14

      Conserved Domains (4) summary
      smart00185
      Location:539 → 574
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:522 → 643
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:204 → 229
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:233 → 272
      Arm; Armadillo/beta-catenin-like repeat

    22. XM_036161022.1 → XP_036016915.1  plakophilin-4 isoform X9

      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:732 → 767
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:715 → 836
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:397 → 422
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:426 → 465
      Arm; Armadillo/beta-catenin-like repeat

    23. XM_036161030.1 → XP_036016923.1  plakophilin-4 isoform X9

      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:732 → 767
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:715 → 836
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:397 → 422
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:426 → 465
      Arm; Armadillo/beta-catenin-like repeat

    24. XM_030250155.2 → XP_030106015.1  plakophilin-4 isoform X6

      Conserved Domains (5) summary
      smart00185
      Location:862 → 897
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:845 → 966
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:527 → 552
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:556 → 595
      Arm; Armadillo/beta-catenin-like repeat
      pfam15449
      Location:74 → 338
      Retinal; Retinal protein

    25. XM_036161016.1 → XP_036016909.1  plakophilin-4 isoform X9

      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:732 → 767
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:715 → 836
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:397 → 422
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:426 → 465
      Arm; Armadillo/beta-catenin-like repeat

    26. XM_036160996.1 → XP_036016889.1  plakophilin-4 isoform X1

      Conserved Domains (5) summary
      smart00185
      Location:880 → 915
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:863 → 984
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:545 → 570
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:574 → 613
      Arm; Armadillo/beta-catenin-like repeat
      pfam03154
      Location:72 → 382
      Atrophin-1; Atrophin-1 family

    27. XM_036161031.1 → XP_036016924.1  plakophilin-4 isoform X9

      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:732 → 767
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:715 → 836
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:397 → 422
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:426 → 465
      Arm; Armadillo/beta-catenin-like repeat

    28. XM_036161054.1 → XP_036016947.1  plakophilin-4 isoform X15

      UniProtKB/TrEMBL
      A2AS47
      Related
      ENSMUSP00000108196.2, ENSMUST00000112577.8
      Conserved Domains (4) summary
      smart00185
      Location:523 → 558
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:506 → 627
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:188 → 213
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:217 → 256
      Arm; Armadillo/beta-catenin-like repeat

    29. XM_036161038.1 → XP_036016931.1  plakophilin-4 isoform X9

      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:732 → 767
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:715 → 836
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:397 → 422
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:426 → 465
      Arm; Armadillo/beta-catenin-like repeat

    30. XM_036161015.1 → XP_036016908.1  plakophilin-4 isoform X9

      Conserved Domains (5) summary
      PLN03209
      Location:72 → 229
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      smart00185
      Location:732 → 767
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:715 → 836
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:397 → 422
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:426 → 465
      Arm; Armadillo/beta-catenin-like repeat

    31. XM_036161048.1 → XP_036016941.1  plakophilin-4 isoform X14

      Conserved Domains (4) summary
      smart00185
      Location:539 → 574
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:522 → 643
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:204 → 229
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:233 → 272
      Arm; Armadillo/beta-catenin-like repeat

    32. XM_036161058.1 → XP_036016951.1  plakophilin-4 isoform X16

      Conserved Domains (4) summary
      smart00185
      Location:522 → 557
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:505 → 626
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:187 → 212
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:216 → 255
      Arm; Armadillo/beta-catenin-like repeat
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q68FH0.1 GenPept UniProtKB/Swiss-Prot:Q68FH0

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