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    Zscan18 zinc finger and SCAN domain containing 18 [ Mus musculus (house mouse) ]

    Gene ID: 232875, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zscan18provided by MGI
    Official Full Name
    zinc finger and SCAN domain containing 18provided by MGI
    Primary source
    MGI:MGI:3643810
    See related
    Ensembl:ENSMUSG00000070822 AllianceGenome:MGI:3643810
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EG232875
    Summary
    Orthologous to human ZSCAN18 (zinc finger and SCAN domain containing 18). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in CNS E18 (RPKM 4.5), CNS E14 (RPKM 2.9) and 19 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zscan18 in Genome Data Viewer
    Location:
    7 A1; 7 7.63 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (12502017..12537565, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (12768090..12811666, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene zinc finger protein 287 pseudogene Neighboring gene dnaJ homolog subfamily B member 6 pseudogene Neighboring gene zinc finger protein 329 pseudogene Neighboring gene STARR-seq mESC enhancer starr_18057 Neighboring gene zinc finger protein 329 Neighboring gene zinc finger protein 110

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders. Li J, et al. Nat Neurosci, 2017 Aug. PMID 28671696, Free PMC Article
    2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    zinc finger and SCAN domain-containing protein 18

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017955.3 → NP_001017955.2  zinc finger and SCAN domain-containing protein 18 isoform 1

      See identical proteins and their annotated locations for NP_001017955.2

      Status: VALIDATED

      Source sequence(s)
      AC161211
      Consensus CDS
      CCDS52021.1
      UniProtKB/TrEMBL
      E9PUD6
      Related
      ENSMUSP00000148239.2, ENSMUST00000211392.2
      Conserved Domains (3) summary
      sd00019
      Location:778 → 798
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02023
      Location:398 → 478
      SCAN; SCAN domain
      pfam05782
      Location:51 → 160
      ECM1; Extracellular matrix protein 1 (ECM1)

    2. NM_001382523.1 → NP_001369452.1  zinc finger and SCAN domain-containing protein 18 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC161211
      UniProtKB/TrEMBL
      E9PUD6
      Related
      ENSMUSP00000147550.2, ENSMUST00000210650.2
      Conserved Domains (3) summary
      sd00019
      Location:778 → 798
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02023
      Location:398 → 478
      SCAN; SCAN domain
      pfam05782
      Location:51 → 160
      ECM1; Extracellular matrix protein 1 (ECM1)

    3. NM_001382524.2 → NP_001369453.1  zinc finger and SCAN domain-containing protein 18 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC161211
      Conserved Domains (3) summary
      PTZ00121
      Location:44 → 396
      PTZ00121; MAEBL; Provisional
      TIGR00927
      Location:43 → 146
      2A1904; K+-dependent Na+/Ca+ exchanger
      pfam02023
      Location:398 → 478
      SCAN; SCAN domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      12502017..12537565 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006539794.5 → XP_006539857.1  zinc finger and SCAN domain-containing protein 18 isoform X3

      See identical proteins and their annotated locations for XP_006539857.1

      UniProtKB/TrEMBL
      E9PUD6
      Conserved Domains (3) summary
      sd00019
      Location:778 → 798
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02023
      Location:398 → 478
      SCAN; SCAN domain
      pfam05782
      Location:51 → 160
      ECM1; Extracellular matrix protein 1 (ECM1)

    2. XM_011250508.4 → XP_011248810.1  zinc finger and SCAN domain-containing protein 18 isoform X3

      See identical proteins and their annotated locations for XP_011248810.1

      UniProtKB/TrEMBL
      E9PUD6
      Conserved Domains (3) summary
      sd00019
      Location:778 → 798
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02023
      Location:398 → 478
      SCAN; SCAN domain
      pfam05782
      Location:51 → 160
      ECM1; Extracellular matrix protein 1 (ECM1)

    3. XM_006539791.5 → XP_006539854.1  zinc finger and SCAN domain-containing protein 18 isoform X2

      Conserved Domains (3) summary
      sd00019
      Location:819 → 839
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02023
      Location:439 → 526
      SCAN; SCAN domain
      pfam09770
      Location:41 → 194
      PAT1; Topoisomerase II-associated protein PAT1

    4. XM_011250509.3 → XP_011248811.1  zinc finger and SCAN domain-containing protein 18 isoform X4

      Conserved Domains (2) summary
      pfam02023
      Location:453 → 540
      SCAN; SCAN domain
      pfam09770
      Location:55 → 208
      PAT1; Topoisomerase II-associated protein PAT1

    5. XM_011250507.3 → XP_011248809.1  zinc finger and SCAN domain-containing protein 18 isoform X1

      Conserved Domains (3) summary
      sd00019
      Location:833 → 853
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02023
      Location:453 → 540
      SCAN; SCAN domain
      pfam09770
      Location:55 → 208
      PAT1; Topoisomerase II-associated protein PAT1

    6. XM_011250510.3 → XP_011248812.1  zinc finger and SCAN domain-containing protein 18 isoform X5

      Conserved Domains (2) summary
      pfam02023
      Location:453 → 540
      SCAN; SCAN domain
      pfam09770
      Location:55 → 208
      PAT1; Topoisomerase II-associated protein PAT1

    RNA

    1. XR_004934062.1 RNA Sequence

    2. XR_004934066.1 RNA Sequence

    3. XR_003946439.2 RNA Sequence

    4. XR_004934068.1 RNA Sequence

    5. XR_004934067.1 RNA Sequence

    6. XR_004934063.1 RNA Sequence

    7. XR_881695.4 RNA Sequence

    8. XR_004934064.1 RNA Sequence

    9. XR_004934065.1 RNA Sequence

    10. XR_004934069.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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