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    Sult6b1 sulfotransferase family, cytosolic, 6B, member 1 [ Mus musculus (house mouse) ]

    Gene ID: 73671, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Sult6b1provided by MGI
    Official Full Name
    sulfotransferase family, cytosolic, 6B, member 1provided by MGI
    Primary source
    MGI:MGI:1920921
    See related
    Ensembl:ENSMUSG00000038045 AllianceGenome:MGI:1920921
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ST6B1; 2410078J06Rik
    Summary
    Predicted to enable sulfotransferase activity. Predicted to be involved in sulfation. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human SULT6B1 (sulfotransferase family 6B member 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    human all
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    Genomic context

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    See Sult6b1 in Genome Data Viewer
    Location:
    17 E3; 17 49.6 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (79192314..79214421, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (78884885..78906992, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E773 Neighboring gene G patch domain containing 11 Neighboring gene eukaryotic translation initiation factor 2-alpha kinase 2 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene Neighboring gene predicted gene, 26637 Neighboring gene STARR-seq mESC enhancer starr_43273 Neighboring gene STARR-positive B cell enhancer ABC_E8698 Neighboring gene CCAAT/enhancer binding protein zeta, opposite strand Neighboring gene CCAAT/enhancer binding protein zeta Neighboring gene STARR-positive B cell enhancer ABC_E5629 Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning, expression and characterization of a novel mouse SULT6 cytosolic sulfotransferase. Takahashi S, et al. J Biochem, 2009 Sep. PMID 19505954
    2. Lineage-specific biology revealed by a finished genome assembly of the mouse. Church DM, et al. PLoS Biol, 2009 May 5. PMID 19468303, Free PMC Article
    3. Mutagenesis of diploid mammalian genes by gene entrapment. Lin Q, et al. Nucleic Acids Res, 2006. PMID 17062627, Free PMC Article
    4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sulfotransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in sulfation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    sulfotransferase 6B1
    Names
    Thyroxine sulfotransferase
    NP_001157097.1
    XP_011244958.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163625.2 → NP_001157097.1  sulfotransferase 6B1

      See identical proteins and their annotated locations for NP_001157097.1

      Status: VALIDATED

      Source sequence(s)
      AC154274
      Consensus CDS
      CCDS50182.1
      UniProtKB/Swiss-Prot
      P0CC03
      UniProtKB/TrEMBL
      E9QNJ5
      Related
      ENSMUSP00000038282.7, ENSMUST00000042683.7
      Conserved Domains (1) summary
      pfam00685
      Location:56 → 289
      Sulfotransfer_1; Sulfotransferase domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      79192314..79214421 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011246656.2 → XP_011244958.1  sulfotransferase 6B1 isoform X1

      Conserved Domains (1) summary
      pfam00685
      Location:5 → 184
      Sulfotransfer_1; Sulfotransferase domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0CC03.1 GenPept UniProtKB/Swiss-Prot:P0CC03

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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