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    Slc25a2 solute carrier family 25 (mitochondrial carrier, ornithine transporter) member 2 [ Mus musculus (house mouse) ]

    Gene ID: 83885, updated on 9-Dec-2024

    Summary

    Official Symbol
    Slc25a2provided by MGI
    Official Full Name
    solute carrier family 25 (mitochondrial carrier, ornithine transporter) member 2provided by MGI
    Primary source
    MGI:MGI:2137907
    See related
    Ensembl:ENSMUSG00000050304 AllianceGenome:MGI:2137907
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ornt2
    Summary
    Predicted to enable L-arginine transmembrane transporter activity; L-lysine transmembrane transporter activity; and L-ornithine transmembrane transporter activity. Predicted to be involved in L-alpha-amino acid transmembrane transport and ornithine metabolic process. Located in mitochondrion. Is expressed in medulla oblongata basal plate mantle layer and pons mantle layer. Orthologous to human SLC25A2 (solute carrier family 25 member 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See Slc25a2 in Genome Data Viewer
    Location:
    18 B3; 18 19.54 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (37770431..37771776, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (37637378..37638723, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene protocadherin alpha 4B Neighboring gene predicted gene, 38666 Neighboring gene predicted gene, 38667 Neighboring gene STARR-seq mESC enhancer starr_44310 Neighboring gene STARR-seq mESC enhancer starr_44311 Neighboring gene protocadherin beta 21 Neighboring gene protocadherin beta 22 Neighboring gene STARR-seq mESC enhancer starr_44313 Neighboring gene STARR-seq mESC enhancer starr_44314 Neighboring gene STARR-positive B cell enhancer ABC_E4245 Neighboring gene protein UXT pseudogene Neighboring gene TATA-box binding protein associated factor 7

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables L-arginine transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables L-lysine transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables L-ornithine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables L-ornithine transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in L-arginine transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in L-lysine transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in L-ornithine transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitochondrial L-ornithine transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitochondrial L-ornithine transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ornithine metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    mitochondrial ornithine transporter 2
    Names
    mitochondrial ornithine transporter
    ornithine transporter 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001159275.1NP_001152747.1  mitochondrial ornithine transporter 2

      See identical proteins and their annotated locations for NP_001152747.1

      Status: VALIDATED

      Source sequence(s)
      AK077159
      Consensus CDS
      CCDS50258.1
      UniProtKB/TrEMBL
      Q99ML6
      Related
      ENSMUSP00000052849.3, ENSMUST00000058635.5
      Conserved Domains (1) summary
      pfam00153
      Location:169261
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      37770431..37771776 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)