Proc-R Proctolin receptor [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Proc-Rprovided by FlyBase
Official Full Name: Proctolin receptorprovided by FlyBase
Primary source: FLYBASE:FBgn0029723
Locus tag: Dmel_CG6986
See related: AllianceGenome:FB:FBgn0029723
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0170980.73; anon-WO0170980.74; CG6986; Dmel\CG6986; Proc R; PROC-R; ProcR
Summary: Enables proctolin receptor activity. Involved in neuropeptide signaling pathway. Located in plasma membrane. Is expressed in head. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (4707916..4729487)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (4601949..4623520)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Genome-wide association in Drosophila identifies a role for Piezo and Proc-R in sleep latency.
Title: Genome-wide association in Drosophila identifies a role for Piezo and Proc-R in sleep latency.
Molecular identification of the first insect proctolin receptor
Title: Molecular identification of the first insect proctolin receptor.
evidence to propose that the orphan G protein-coupled receptor CG6986 of Drosophila is a proctolin receptor
Title: Identification and characterization of a G protein-coupled receptor for the neuropeptide proctolin in Drosophilamelanogaster.

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables G protein-coupled receptor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables neuropeptide receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables neuropeptide receptor activity	ISM Inferred from Sequence Model more info	PubMed
enables proctolin receptor activity	IDA Inferred from Direct Assay more info	PubMed
enables proctolin receptor activity	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in G protein-coupled receptor signaling pathway	ISM Inferred from Sequence Model more info	PubMed
involved_in G protein-coupled receptor signaling pathway	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in neuropeptide signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in neuropeptide signaling pathway	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	ISM Inferred from Sequence Model more info	PubMed
located_in membrane	ISS Inferred from Sequence or Structural Similarity more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed