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    Ir87a Ionotropic receptor 87a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41654, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ir87aprovided by FlyBase
    Official Full Name
    Ionotropic receptor 87aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038153
    Locus tag
    Dmel_CG14376
    See related
    AllianceGenome:FB:FBgn0038153
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    87a; CG14376; DmelIR87a; Dmel\CG14376; IR87a
    Summary
    Predicted to enable ligand-gated monoatomic ion channel activity. Predicted to be involved in detection of chemical stimulus. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ir87a in Genome Data Viewer
    Location:
    87E10-87E11; 3-53 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (13420279..13423140)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (9246001..9248862)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene yellow-e2 Neighboring gene yellow-e Neighboring gene long non-coding RNA:CR45591 Neighboring gene Actin 87E Neighboring gene yurt

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mechanisms underlying the cooperation between loss of epithelial polarity and Notch signaling during neoplastic growth in Drosophila. Logeay R, et al. Development, 2022 Feb 1. PMID 35005772
    2. Molecular phylogeny of the antiangiogenic and neurotrophic serpin, pigment epithelium derived factor in vertebrates. Xu X, et al. BMC Genomics, 2006 Oct 4. PMID 17020603, Free PMC Article
    3. A Molecular and Cellular Context-Dependent Role for Ir76b in Detection of Amino Acid Taste. Ganguly A, et al. Cell Rep, 2017 Jan 17. PMID 28099851, Free PMC Article
    4. An expression atlas of variant ionotropic glutamate receptors identifies a molecular basis of carbonation sensing. Sánchez-Alcañiz JA, et al. Nat Commun, 2018 Oct 12. PMID 30315166, Free PMC Article
    5. The Female Post-Mating Response Requires Genes Expressed in the Secondary Cells of the Male Accessory Gland in Drosophila melanogaster. Sitnik JL, et al. Genetics, 2016 Mar. PMID 26746709, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated monoatomic ion channel activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ionotropic receptor 87a
    Names
    CG14376-PB
    Ir87a-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      13420279..13423140
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142033.2 → NP_650290.2  ionotropic receptor 87a [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650290.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VFV0
      Conserved Domains (1) summary
      cl21456
      Location:408 → 475
      Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VFV0 Q9VFV0

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