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    Sgp Sgroppino [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34188, updated on 17-Dec-2024

    Summary

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    Official Symbol
    Sgpprovided by FlyBase
    Official Full Name
    Sgroppinoprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032055
    Locus tag
    Dmel_CG13091
    See related
    AllianceGenome:FB:FBgn0032055
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13091; CT32316; Dmel\CG13091; sgp
    Summary
    Predicted to enable alcohol-forming very long-chain fatty acyl-CoA reductase activity. Predicted to be involved in long-chain fatty-acyl-CoA metabolic process. Located in peroxisomal membrane. Is expressed in adult fat body; adult head; and adult heart. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Sgp in Genome Data Viewer
    Location:
    29D4-29D4; 2-33 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8519690..8521809)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8519690..8521809)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Phosphatidylinositol glycan anchor biosynthesis class U Neighboring gene mitochondrial ribosomal protein L51 Neighboring gene Ubiquitin-like activating enzyme 4 Neighboring gene Angiotensin-converting enzyme-related Neighboring gene lemming B Neighboring gene lemming A Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila melanogaster positive transcriptional elongation factors regulate metabolic and sex-biased expression in adults. Yang H, et al. BMC Genomics, 2017 May 18. PMID 28521739, Free PMC Article
    2. The SILAC fly allows for accurate protein quantification in vivo. Sury MD, et al. Mol Cell Proteomics, 2010 Oct. PMID 20525996, Free PMC Article
    3. Peroxisome-associated Sgroppino links fat metabolism with survival after RNA virus infection in Drosophila. Merkling SH, et al. Sci Rep, 2019 Feb 14. PMID 30765784, Free PMC Article
    4. A postbiotic from Aspergillus oryzae attenuates the impact of heat stress in ectothermic and endothermic organisms. Kaufman JD, et al. Sci Rep, 2021 Mar 19. PMID 33742039, Free PMC Article
    5. Birth-and-Death Evolution of the Fatty Acyl-CoA Reductase (FAR) Gene Family and Diversification of Cuticular Hydrocarbon Synthesis in Drosophila. Finet C, et al. Genome Biol Evol, 2019 Jun 1. PMID 31076758, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables alcohol-forming long-chain fatty acyl-CoA reductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables alcohol-forming very long-chain fatty acyl-CoA reductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables alcohol-forming very long-chain fatty acyl-CoA reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in long-chain fatty-acyl-CoA metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in peroxisomal membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    is_active_in peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    sgroppino
    Names
    CG13091-PA
    CG13091-PB
    Sgp-PA
    Sgp-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      8519690..8521809
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273328.1 → NP_001260257.1  sgroppino, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260257.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0I7, Q9VLJ7
      Conserved Domains (3) summary
      cd09071
      Location:367 → 457
      FAR_C; C-terminal domain of fatty acyl CoA reductases
      cd05236
      Location:12 → 333
      FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
      PLN02996
      Location:1 → 449
      PLN02996; fatty acyl-CoA reductase

    2. NM_135397.3 → NP_609241.1  sgroppino, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609241.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0I7, Q9VLJ7
      Related
      FBpp0079296
      Conserved Domains (3) summary
      cd09071
      Location:367 → 457
      FAR_C; C-terminal domain of fatty acyl CoA reductases
      cd05236
      Location:12 → 333
      FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
      PLN02996
      Location:1 → 449
      PLN02996; fatty acyl-CoA reductase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VLJ7 Q9VLJ7

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