RpL11 Ribosomal protein L11 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: RpL11provided by FlyBase
Official Full Name: Ribosomal protein L11provided by FlyBase
Primary source: FLYBASE:FBgn0013325
Locus tag: Dmel_CG7726
See related: AllianceGenome:FB:FBgn0013325
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:LD17235; CG7726; chr2R:14957112..14957299; DL11; Dmel\CG7726; EST A; l(2)k16914; L11; L5; Rp L11; RPL11
Summary: A structural constituent of ribosome. Predicted to be involved in translation. Located in cytosolic ribosome and nucleolus. Colocalizes with nuclear chromosome and polytene chromosome puff. Is expressed in adult head and adult heart. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 7 and T-cell acute lymphoblastic leukemia. Orthologous to human RPL11 (ribosomal protein L11). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (19442342..19443825)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (15329847..15331330)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables structural constituent of ribosome	HDA more info	PubMed
enables structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IDA Inferred from Direct Assay more info	PubMed
enables structural constituent of ribosome	IEA Inferred from Electronic Annotation more info
enables structural constituent of ribosome	TAS Traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in cytoplasmic translation	IC Inferred by Curator more info	PubMed
involved_in cytoplasmic translation	TAS Traceable Author Statement more info	PubMed
involved_in translation	IBA Inferred from Biological aspect of Ancestor more info
involved_in translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
part_of cytosolic large ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
part_of cytosolic large ribosomal subunit	TAS Traceable Author Statement more info	PubMed
located_in cytosolic ribosome	HDA more info	PubMed
located_in cytosolic ribosome	IDA Inferred from Direct Assay more info	PubMed
colocalizes_with nuclear chromosome	IDA Inferred from Direct Assay more info	PubMed
located_in nucleolus	IDA Inferred from Direct Assay more info	PubMed
colocalizes_with polytene chromosome puff	IDA Inferred from Direct Assay more info	PubMed
located_in ribosome	IEA Inferred from Electronic Annotation more info

Names: 60S ribosomal protein L11; CG7726-PA; CG7726-PB; RpL11-PA; RpL11-PB; ribosomal protein DL11

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