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    Fam210b family with sequence similarity 210, member B [ Mus musculus (house mouse) ]

    Gene ID: 67017, updated on 9-Dec-2024

    Summary

    Official Symbol
    Fam210bprovided by MGI
    Official Full Name
    family with sequence similarity 210, member Bprovided by MGI
    Primary source
    MGI:MGI:1914267
    See related
    Ensembl:ENSMUSG00000027495 AllianceGenome:MGI:1914267
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2010011I20Rik
    Summary
    Predicted to be involved in cellular response to estradiol stimulus and positive regulation of erythrocyte differentiation. Predicted to be located in mitochondrial outer membrane. Predicted to be active in mitochondrion. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and immune system. Used to study systemic lupus erythematosus. Orthologous to human FAM210B (family with sequence similarity 210 member B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in liver E14.5 (RPKM 40.7), liver E14 (RPKM 39.7) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Fam210b in Genome Data Viewer
    Location:
    2 H3; 2 94.83 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (172187444..172197669)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (172345570..172355749)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 40008 Neighboring gene predicted gene 14275 Neighboring gene STARR-seq mESC enhancer starr_06571 Neighboring gene predicted gene 14273 Neighboring gene aurora kinase A Neighboring gene cleavage stimulation factor, 3' pre-RNA, subunit 1 Neighboring gene STARR-seq mESC enhancer starr_06572 Neighboring gene STARR-positive B cell enhancer ABC_E823 Neighboring gene Cas scaffolding protein family member 4 Neighboring gene uncharacterized LOC118568483 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:172259262-172259485

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2)  1 citation
    • Targeted (2) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in mitochondrial outer membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial outer membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    protein FAM210B, mitochondrial
    Names
    transmembrane protein C20orf108 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025912.4NP_080188.3  protein FAM210B, mitochondrial

      See identical proteins and their annotated locations for NP_080188.3

      Status: VALIDATED

      Source sequence(s)
      AI504401, AK149497, AK160529
      Consensus CDS
      CCDS17128.1
      UniProtKB/Swiss-Prot
      Q3UFZ3, Q91WA2, Q9D8B6
      UniProtKB/TrEMBL
      Q3UFK7
      Related
      ENSMUSP00000028995.5, ENSMUST00000028995.5
      Conserved Domains (1) summary
      pfam06916
      Location:85172
      DUF1279; Protein of unknown function (DUF1279)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      172187444..172197669
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006500059.2XP_006500122.1  protein FAM210B, mitochondrial isoform X1

      See identical proteins and their annotated locations for XP_006500122.1

      UniProtKB/Swiss-Prot
      Q3UFZ3, Q91WA2, Q9D8B6
      UniProtKB/TrEMBL
      Q3UFK7
      Conserved Domains (1) summary
      pfam06916
      Location:85172
      DUF1279; Protein of unknown function (DUF1279)