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    Dmrta1 DMRT-like family A1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 313352, updated on 9-Dec-2024

    Summary

    Official Symbol
    Dmrta1provided by RGD
    Official Full Name
    DMRT-like family A1provided by RGD
    Primary source
    RGD:1309796
    See related
    EnsemblRapid:ENSRNOG00000024093 AllianceGenome:RGD:1309796
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II and sex differentiation. Predicted to act upstream of or within male mating behavior and ovarian follicle development. Predicted to be active in nucleus. Orthologous to human DMRTA1 (DMRT like family A1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 26.2), Muscle (RPKM 5.7) and 4 other tissues See more
    Orthologs
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    Genomic context

    See Dmrta1 in Genome Data Viewer
    Location:
    5q32
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (109531704..109538244)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (104415893..104422433)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (108278217..108284757)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479007 Neighboring gene uncharacterized LOC103692411 Neighboring gene lamin tail domain containing 1, pseudogene 1 Neighboring gene ribosomal protein S24, pseudogene 18

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within male mating behavior ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within ovarian follicle development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in sex differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    doublesex- and mab-3-related transcription factor A1
    Names
    doublesex and mab-3 related transcription factor like family A1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107945.1NP_001101415.1  doublesex- and mab-3-related transcription factor A1

      See identical proteins and their annotated locations for NP_001101415.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473998
      UniProtKB/TrEMBL
      A6JRF5, D3ZIZ0
      Related
      ENSRNOP00000032876.4, ENSRNOT00000038972.6
      Conserved Domains (2) summary
      pfam00751
      Location:80126
      DM; DM DNA binding domain
      pfam03474
      Location:313348
      DMA; DMRTA motif

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      109531704..109538244
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)