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    Wdr53 WD repeat domain 53 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498097, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Wdr53provided by RGD
    Official Full Name
    WD repeat domain 53provided by RGD
    Primary source
    RGD:1559546
    See related
    EnsemblRapid:ENSRNOG00000001754 AllianceGenome:RGD:1559546
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1559546
    Summary
    Orthologous to human WDR53 (WD repeat domain 53). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 51.5), Thymus (RPKM 27.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Wdr53 in Genome Data Viewer
    Location:
    11q22
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (82047674..82056217, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (68542647..68551148, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (71787454..71796258, complement)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 168 Neighboring gene single-pass membrane protein with coiled-coil domains 1 Neighboring gene small nucleolar RNA SNORA79 Neighboring gene F-box protein 45 Neighboring gene uncharacterized LOC134481089 Neighboring gene uncharacterized LOC120095670

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    WD repeat-containing protein 53

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109055.2 → NP_001102525.1  WD repeat-containing protein 53

      See identical proteins and their annotated locations for NP_001102525.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      A0A8I5ZLS1, A6IRS7, D4ADI9
      Related
      ENSRNOP00000002392.3, ENSRNOT00000002392.6
      Conserved Domains (2) summary
      sd00039
      Location:13 → 49
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:8 → 269
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. NM_001399295.1 → NP_001386224.1  WD repeat-containing protein 53

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      A0A8I5ZLS1, A6IRS7, D4ADI9
      Conserved Domains (2) summary
      sd00039
      Location:13 → 49
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:8 → 269
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    3. NM_001399296.1 → NP_001386225.1  WD repeat-containing protein 53

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      A0A8I5ZLS1, A6IRS7, D4ADI9
      Conserved Domains (2) summary
      sd00039
      Location:13 → 49
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:8 → 269
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      82047674..82056217 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063270707.1 → XP_063126777.1  WD repeat-containing protein 53 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZLS1, A6IRS7, D4ADI9

    2. XM_017598046.3 → XP_017453535.1  WD repeat-containing protein 53 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZLS1, A6IRS7, D4ADI9
      Conserved Domains (2) summary
      sd00039
      Location:13 → 49
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:8 → 269
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    3. XM_063270708.1 → XP_063126778.1  WD repeat-containing protein 53 isoform X3

    4. XM_039088581.2 → XP_038944509.1  WD repeat-containing protein 53 isoform X3

      Conserved Domains (2) summary
      sd00039
      Location:40 → 78
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:40 → 124
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    5. XM_039088580.2 → XP_038944508.1  WD repeat-containing protein 53 isoform X2

      Conserved Domains (2) summary
      COG2319
      Location:30 → 183
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:36 → 72
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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