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    Wfdc21 WAP four-disulfide core domain 21 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 360228, updated on 9-Dec-2024

    Summary

    Official Symbol
    Wfdc21provided by RGD
    Official Full Name
    WAP four-disulfide core domain 21provided by RGD
    Primary source
    RGD:1303147
    See related
    EnsemblRapid:ENSRNOG00000029668 AllianceGenome:RGD:1303147
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in antibacterial humoral response and innate immune response. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 604.4), Lung (RPKM 59.8) and 3 other tissues See more
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    Genomic context

    See Wfdc21 in Genome Data Viewer
    Location:
    10q26
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (69125336..69131205)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (68627836..68633705)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (71047326..71053195)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene anosmin 1, pseudogene 1 Neighboring gene WAP four-disulfide core domain 18 Neighboring gene HEAT repeat containing 6 Neighboring gene HNF1 homeobox B Neighboring gene uncharacterized LOC134480708

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in antibacterial humoral response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    WDNM1-like protein
    Names
    WDNM1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003706.3NP_001003706.2  WDNM1-like protein precursor

      See identical proteins and their annotated locations for NP_001003706.2

      Status: VALIDATED

      Source sequence(s)
      AW530516, BG661061
      UniProtKB/TrEMBL
      A1EC93, A1EC94, A6HHJ1, F7F765, Q6BEA3
      Related
      ENSRNOP00000049454.2, ENSRNOT00000042643.4

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      69125336..69131205
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)