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    UTP30 Utp30p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853934, updated on 9-Dec-2024

    Summary

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    Official Symbol
    UTP30
    Official Full Name
    Utp30p
    Primary source
    SGD:S000001768
    Locus tag
    YKR060W
    See related
    AllianceGenome:SGD:S000001768; FungiDB:YKR060W; VEuPathDB:YKR060W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable RNA binding activity. Involved in ribosomal small subunit biogenesis. Located in nucleolus. Part of 90S preribosome. Orthologous to human RSL1D1 (ribosomal L1 domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See UTP30 in Genome Data Viewer
    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (556518..557342)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene glycogenin glucosyltransferase GLG1 Neighboring gene translation initiation factor eIF4A Neighboring gene mannosyltransferase KTR2 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure and RNA recognition of ribosome assembly factor Utp30. Hu J, et al. RNA, 2017 Dec. PMID 28951391, Free PMC Article
    2. Genetic interactions of yeast NEP1 (EMG1), encoding an essential factor in ribosome biogenesis. Schilling V, et al. Yeast, 2012 May. PMID 22588997
    3. Predicting protein functions from redundancies in large-scale protein interaction networks. Samanta MP, et al. Proc Natl Acad Sci U S A, 2003 Oct 28. PMID 14566057, Free PMC Article
    4. 90S pre-ribosome transformation into the primordial 40S subunit. Cheng J, et al. Science, 2020 Sep 18. PMID 32943521
    5. Fcf1p and Fcf2p are novel nucleolar Saccharomyces cerevisiae proteins involved in pre-rRNA processing. Rempola B, et al. Biochem Biophys Res Commun, 2006 Jul 28. PMID 16762320

    See all (52) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ribosomal small subunit biogenesis IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of 90S preribosome HDA PubMed 
    located_in nucleolus HDA PubMed 
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Utp30p
    NP_012986.1
    • Subunit of U3-containing 90S preribosome complex; complex is involved in production of 18S rRNA and assembly of small ribosomal subunit; Utp30p is peripherally associated with 90S preribosome and appears partially redundant with its paralog Cic1p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      556518..557342
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179850.1 → NP_012986.1  TPA: Utp30p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012986.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VXC1, P36144
      UniProtKB/TrEMBL
      B3LRD5, B5VMK7, C7GX79, C8ZCM3, G2WI88, N1P847
      Conserved Domains (1) summary
      pfam00687
      Location:31 → 249
      Ribosomal_L1; Ribosomal protein L1p/L10e family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P36144.1

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