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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853309, updated on 9-Dec-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000003668
    Locus tag
    YJL132W
    See related
    AllianceGenome:SGD:S000003668; FungiDB:YJL132W; VEuPathDB:YJL132W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable glycosylphosphatidylinositol phospholipase D activity. Predicted to be involved in GPI anchor release. Located in membrane. Orthologous to human GPLD1 (glycosylphosphatidylinositol specific phospholipase D1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (161914..164166)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Dpi8p Neighboring gene Fe(2+) transporter Neighboring gene Aim23p Neighboring gene bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide characterization of the Zap1p zinc-responsive regulon in yeast. Lyons TJ, et al. Proc Natl Acad Sci U S A, 2000 Jul 5. PMID 10884426, Free PMC Article
    2. Sequence-based approach for identification of cell wall proteins in Saccharomyces cerevisiae. Terashima H, et al. Curr Genet, 2002 Feb. PMID 11935221
    3. Identifying Interaction Partners of Yeast Protein Disulfide Isomerases Using a Small Thiol-Reactive Cross-Linker: Implications for Secretory Pathway Proteostasis. Freije BJ, et al. Chem Res Toxicol, 2022 Feb 21. PMID 35084835, Free PMC Article
    4. Comprehensive and quantitative mapping of RNA-protein interactions across a transcribed eukaryotic genome. She R, et al. Proc Natl Acad Sci U S A, 2017 Apr 4. PMID 28325876, Free PMC Article
    5. Functional profiling of the Saccharomyces cerevisiae genome. Giaever G, et al. Nature, 2002 Jul 25. PMID 12140549

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables glycosylphosphatidylinositol phospholipase D activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in fungal-type vacuole HDA PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_012403.1
    • hypothetical protein; localizes to the membrane fraction; possible Zap1p-regulated target gene induced by zinc deficiency; YJL132W is a non-essential gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      161914..164166
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181565.1 → NP_012403.1  TPA: uncharacterized protein YJL132W [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012403.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VW53, P47014
      UniProtKB/TrEMBL
      G2WGN9
      Conserved Domains (2) summary
      smart00191
      Location:334 → 374
      Int_alpha; Integrin alpha (beta-propellor repeats)
      pfam00882
      Location:35 → 234
      Zn_dep_PLPC; Zinc dependent phospholipase C
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P47014.1

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